การเปรียบเทียบระดับวิตามินดีและแมกนีเซียมในเลือดผู้ป่วย ไฟโบรมัยอัลเจียกับคนปกติ

การเปรียบเทียบระดับวิตามินดีและแมกนีเซียมในเลือดผู้ป่วย ไฟโบรมัยอัลเจียกับคนปกติ

Authors

  • ศุภรัศมิ์ ทวนนวรัตน์
  • ประดิษฐ์ ประทีปะวณิช
  • นิลรัตน์ วรรณศิลป์
  • ภูมิ สุขธิติพัฒน์

Keywords:

fibromyalgia, vitamin D, magnesium

Abstract

Objectives: To compare serum total vitamin D (25(OH) D) levels and plasma magnesium levels between patients with fibromyalgia syndrome (FMS) and age and sex matched normal control population.

Study design: Age and sex matched cross-sectional study

Setting: Out patients of Department of Rehabilitation Medicine, Faculty of Medicine Siriraj hospital

Subjects: A total of 40 FMS patients diagnosed by the ACR 2010 criteria and 40 age and sex matched normal controls (mean age = 45 years, 36 females and 4 males in each groups) from August to October 2014. All participants had no underlying disease and did not take any medication, vitamin D or magnesium supplement influencing the laboratory results.

Methods: Participants’ blood was collected for total serumvitamin D and plasma magnesium levels. The results werecompared between each group.

Results: The mean value of serum total serum vitamin D concentration in FMS group was 0.5 (SD 0.1) ng/mL higher than normal controls (mean 24.6 (SD 7.5) and 24.1 (SD 8.5) ng/mL, respectively, p=0.813). The mean value of plasma magnesium levels was 0.1 (SD 0.02) mg/dL higher in fibromyalgia group than control [mean 2.1 (SD 0.18) and 2.0 (SD 0.16) mg/dL, respectively, p=0.108).

Conclusion: There was no statistically significant difference in mean total serum vitamin D and plasma magnesium levels between fibromyalgia and control group.

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Published

2016-12-30