Prevalence and Potential Associated Factors of Poststroke Depression
Keywords:depression, disability, prevalence, stroke
Objectives: To study the prevalence and potential associated factors of poststroke depression (PSD).
Study design: Cross-sectional study.
Setting: Department of Rehabilitation Medicine, Faculty of Medicine Siriraj Hospital, Bangkok, Thailand.
Subjects: First ever stroke patients age 45 years old with duration of stroke from 2 weeks to 2 years.
Methods: The included patients were assessed with the Barthel Index (BI) and the Modified Rankin Scale for Neurologic Disability (MRS). A psychiatric interview according to the diagnostic and statistical manual of mental disorders classification, fifth edition (DSM-5TM) criteria was performed by a psychiatrist. Prevalence was described and potential associated factors of PSD were analyzed with multivariate forward stepwise logistic regression.
Results: Of 115 patients, there were 63 males (54.8%). Mean age was 64 (SD 10) years old. Median duration of stroke was 59 days. The prevalence of PSD was 20%, 8 of them (6.9%) were diagnosed with major depressive disorder and 15 of them (13.1%) had other depressive disorder. The univariate analysis revealed those with PSD were more disabled according to the MRS (p = 0.04) and had more dependent grooming according to the BI (p = 0.003). With multivariate analysis,only grooming was associated with PSD (odd ratio 4.9; 95%CI 1.6-14.8).
Conclusion: The prevalence of poststroke depression within the first 2 years of those with the first stroke and aged 45 years or older was 20%. Dependence in grooming was the only factor significantly associated with poststroke depression.
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