Guillain Barre syndrome associated with COVID-19 infection


  • Chaiwat Klinhom-on


Guillain Barre syndrome, Covid19


          Guillain Barre syndrome is a disorder involving a numbness, weakness, or
weakness of the cranial nerves caused by an inflammation of the peripheral
nerves or spinal nerve roots as a result of a bacterial or viral infection. Patients
may have mild or severe symptoms that can lead to respiratory failure requiring
mechanical ventilation, or even so severe that it can lead to death. Since the end
of 2019, with the Covid 19 outbreak spreading in many countries around the
world, although the Covid 19 virus mainly affects the respiratory system, it has
been found that there are patients with false neurological symptoms both during
the Covid19 infection and follows after the respiratory infection has been cured.
Guillain Barre syndrome is found to be one of the neurological symptoms
associated with infection with Covid19, a newly found outbreak of the virus, and
we do not currently know about the relationship between this virus and its effects
to the entire nervous system. Therefore, it is necessary to collect information to
be useful in understanding the pathogenesis of the Covid19 virus in the future.


Robert B. Darooff, Gerald M. Fenichel. Bradley’s Neurology in clinical practice 7th

Edition , 2016;1955-1964

Willison HJ, Jacobs BC, van Doorn PA, et al. Guillain-Barré syndrome. The Lancet


SajidHameed, Ayisha FarooqKhan, SaraKhan. Electrodiagnostic findings in COVID-patients: A single center experience. Clinical Neurophysiology 2021 ;3019-3024

James B. Caress MD,Ryan J. Castoro DO,Zachary Simmons MD .COVID-19–associated Guillain-Barré syndrome: The early pandemic experience. Muscle and nerve . Volume62, Issue4 October 2020 ; 485-491

P. Zuberbühler, M.E. Conti, L. León-Cejas, F. Maximiliano-González, . Guillain-Barré syndrome associated to COVID-19 infection: a review of published case reports. Neurología 2021 ; 72(6):203-212

Sindhuja Korem , Haresh Gandhi , Decerie Baculi Dayag . Guillain-Barré syndrome associated withCOVID-19 disease . BMJ Case Rep 2020

Zhao H, Shen D, Zhou H, et al. Guillain-Barré syndrome associated with SARS-CoV-2infection: causality or coincidence? The Lancet Neurology 2020;19:383–4

Leyla Baysal-Kirac, Hilmi Uysal. COVID-19 Associate Neurological Complications. Neurological Sciences and Neurophysiology Volume 37 January-March 2020 ; 37:1-3

Gianpaolo Toscano, M.D. , Francesco Palmerini, M.D. , Sabrina Ravaglia, M.D., Ph.D. Guillain–Barré Syndrome Associated with SARS-CoV-2. N Engl J Med 2020;382:2574-2576

UddalakChakraborty, ArkapravoHati, AtanuChandra. Covid-19 associated Guillain- Barré syndrome: A series of a relatively uncommon neurological complication. Diabetes & Metabolic Syndrome Volume 15, Issue 6, November–December 2021, 102326

Ankit Gupta . Is COVID-19-related Guillain-Barré syndrome different. Brain, Behavior, and Immunity. July 2020, Pages 177-178




How to Cite

Chaiwat Klinhom-on. (2022). Guillain Barre syndrome associated with COVID-19 infection. Saraburi Hospital Medical Journal, 35(1), 8–15. Retrieved from