Efficacy of Intravenous Glucose for Preventing Postoperative Nausea and Vomiting after Abdominal Hysterectomy under General Anesthesia

Intravenous Glucose in Prevention of Post-operative Nausea and Vomiting

Authors

  • Chanatthee Kitsiripant Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Thadakorn Tantisarasart Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Wirat Wasinwong Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Ngamjit Pattaravit Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Maliwan Oofuwong Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Aroontip Limsathianchai Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
  • Sukanya Kaewsridam Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.

DOI:

https://doi.org/10.31584/psumj.2022249355

Keywords:

Intravenous glucose, Postoperative nausea and vomiting, Total abdominal hysterctomy

Abstract

Objective: This study aimed to evaluate the ability of intravenous glucose administration during the maintenance of anesthesia as an alternative method for diminishing the incidence of postoperative nausea and vomiting (PONV) in patients undergoing total abdominal hysterectomy (TAH).
Material and Methods: This was a prospective, double-blind randomized placebo-controlled trial. One hundred and ten patients who were 18 - 65 years old, American Society of Anesthesiology (ASA) 1 or 2 and required general anesthesia for TAH, were divided randomly to receive 5% DNSS (Group D) or normal saline (Group N) as a maintenance fluid at a rate of 2 mL/kg/hr. The primary outcome was the incidence of PONV at the arrival time in post-anesthetic care unit (PACU). The secondary outcomes were severity of PONV, time to first dose of an antiemetic drug, amount of antiemetic dose, and length of stay in the hospital.
Results: The incidence of PONV in group N was 5.5% and in group D was 10.4% (p-value = 0.360). There were no statistically significant differences regarding the VRS scores, time to the first dose of antiemetic drug, the amount of antiemetic drug, and length of hospital stay between the 2 groups.
Conclusions: There was no significant difference in efficacy between intravenous glucose administration and placebo in the prevention of PONV in patients undergoing abdominal hysterectomy under general anesthesia.

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Published

2022-01-24 — Updated on 2022-02-03

How to Cite

1.
Kitsiripant C, Tantisarasart T, Wasinwong W, Pattaravit N, Oofuwong M, Limsathianchai A, Kaewsridam S. Efficacy of Intravenous Glucose for Preventing Postoperative Nausea and Vomiting after Abdominal Hysterectomy under General Anesthesia: Intravenous Glucose in Prevention of Post-operative Nausea and Vomiting. PSU Med J [Internet]. 2022 Feb. 3 [cited 2024 Apr. 19];2(1):15-23. Available from: https://he01.tci-thaijo.org/index.php/PSUMJ/article/view/249355

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Vol. 2 No. 1 (2022): Jan-Apr

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Original Articles

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