A Case Report of Disseminated Sporotrichosis in A Healthy Elderly

Authors

  • Parissada Anugoolgarn Department of Internal Medicine, Maharaj Nakhon Si Thammarat Hospital

Keywords:

Disseminated Sporotrichosis, Healthy, Non-HIV

Abstract

Sporotrichosis is caused by a dimorphic fungus known as Sporothrix schenckii. Lymphocutaneous disease is the most common form and rarely disseminated form. We report a 62-year-old Thai man who presented with insidious onset fever for 3 weeks with generalized papulonecrotic lesions on the face, trunk, extremities, and splenomegaly that had not responded to a course of antibiotics. He has no significant past medical illness and no history of recurrent infection or immunosuppressive drug use. Importantly, anti-HIV was negative. Skin biopsy revealed Histoplasma capsulatum. His atypical presentation led to a doubtful diagnosis. He was repeatedly scraped and found yeast cells and cigar-shaped bodies. Subsequently, 18S rRNA identified Sporothrix schenckii. Compatible with disseminated sporotrichosis. The IFN-gamma autoantibody and CD4/CD8 level were normal. He had no recent travel. However, his couple has been raising eight cats around in their home for over a decade. They prescribed 4 weeks of Amphotericin B and 1 year of itraconazole for treatment. The lesion improves gradually.

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Published

2024-12-31

How to Cite

1.
Anugoolgarn P. A Case Report of Disseminated Sporotrichosis in A Healthy Elderly. MNST Med J [internet]. 2024 Dec. 31 [cited 2025 Dec. 30];8(2):147-53. available from: https://he01.tci-thaijo.org/index.php/MNSTMedJ/article/view/276288