Eeffects of Triphala herbal formula in obesity stage 1subjects at Maharaj nakhon si thammarat hospital.

Abstract

Introduction:  Obesity is importance health problem and increasing prevalence every year. Its impacts were both physical and mental health as well as quality of life in patients. Treatment of obesity emphasized in nutritional control, physical activity and behavioral adaptation. Triphala is worldwide usage herbal formula and was increased interest. In animal study Triphala showed decreasing body weight, visceral fat, triglyceride level and LDL-cholesterol but increasing HDL-cholesterol.

Objective: Purposes of this study were to explore the effects of Triphala on body mass index, waist circumference, fasting blood sugar, Hemoglobin A1C, triglyceride, LDL-cholesterol and quality of life in obesity stage 1 subjects.

Materials and Methods: The study was double-blind randomized control trail. The forty volunteers were randomized into two groups, twenty persons is study group take Triphala herbal formula 1800 mg per day and twenty persons is control group take placebo drug. Body mass index , fasting blood sugar, Hemoglobin A1C, triglyceride, LDL-cholesterol and WHO-quality of life questionnaire were compared before and after 8 weeks.

Results: By using Wilcoxon Signed Ranks Test at 95% confidence level, compared variables before and after taken herbal drugs in each groups. In study group, waist circumference and Hemoglobin A1C were statistically significant change. In control group Hemoglobin A1C were statistically significant change. Other variables were no statistically significant change.  But Triphala herbal formula was no statistically significant change in body mass index, waist circumference, fasting blood sugar, Hemoglobin A1C, triglyceride, LDL-cholesterol and quality of life in obesity stage 1 subjects compared with placebo drugs by using Mann-Whitney U test at 95% confidence level.