The Use of Methamphetamine During Pregnancy on Maternal and Neonatal Health Outcomes: A Retrospective Study in Tertiary Hospital
Keywords:
preterm labor, low birth weight, birth asphyxia, MethamphetamineAbstract
Background: Methamphetamine use during pregnancy is a public health problem and is associated with obstetric complications and undesirable newborn outcomes.
Objective: To compare maternal and newborn health outcomes between pregnant women with and without a history of methamphetamine use during pregnancy.
Materials and Methods: A Retrospective Analytical Study of medical records of singleton deliveries in Maharaj Nakhon Si Thammarat Hospital between October 2023 to September 2025. A total of 6,989 cases were divided into 98 cases with a history of methamphetamine use and 6,891 cases without a history of methamphetamine use. Data were analyzed with descriptive statistics, Chi-square test and Fisher's exact test. Statistical significance is defined at p < .05
Results: 1.40% of pregnant women with a history of methamphetamine use were found. This group had a statistically significant higher rate of preterm labor than group without a history of methamphetamine use (32.65% and 11.84%, respectively; p<.001). In addition, Newborns born to mothers with a history of methamphetamine use had a statistically significant low birth weight than mothers without a history of methamphetamine use (19.40% and 10.61%, respectively; p = .005), as well as birth asphyxia and referral to Neonatal Intensive Care Unit (NICU) statistically significantly higher than newborns born to mothers without a history of methamphetamine use. (p < .001)
Conclusion: Methamphetamine use during pregnancy is associated with adverse maternal and newborn outcomes. Especially, preterm labor, low birth weight, birth asphyxia and newborn care in NICU.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในมหาราชนครศรีธรรมราชเวชสาร ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใด ๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในมหาราชนครศรีธรรมราชเวชสาร ถือเป็นลิขสิทธิ์ของมหาราชนครศรีธรรมราชเวชสาร หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใด จะต้องได้รับอนุญาตเป็นลายลักษณ์อักษรจากวารสารมหาราชนครศรีธรรมราชเวชสาร ก่อนเท่านั้น
