Success Rate Methotrexate in Management of Ectopic Pregnancy at Maharaj Nakhon Si Thammarat Hospital
Keywords:
Ectopic pregnancy, efficacy, success rate, complication, MethotrexateAbstract
Background: Ectopic pregnancy is an urgency to emergency condition that requires prompt diagnosis and treatment. The survival rate is high, and complications are minimal if the condition is diagnosed quickly and accurately. Methotrexate is an alternative treatment option for patients with ectopic pregnancy who have no contraindications to the drug. Evaluating the success rate and identifying the factors associated with successful treatment are crucial to improving the effectiveness of management strategies.
Objective: To determine the success rate and the factors influencing the treatment of ectopic pregnancy with Methotrexate at Maharaj Nakhon Si Thammarat Hospital, Nakhon Si Thammarat Province.
Materials and methods: A retrospective study was conducted by reviewing medical records of patients with ectopic pregnancy who received Methotrexate treatment at the hospital between January 1, 2018, and December 31, 2023.
Result: Of the 82 patients treated with Methotrexate, the overall success rate was 84.14%. Serum beta-human chorionic gonadotropin (beta-hCG) level was significantly associated with treatment success (OR 9.48, 95% CI = 2.1-42.84, P = 0.001).
Conclusion: Medical management of ectopic pregnancy using Methotrexate demonstrates a success rate of 84.14%. The serum beta-hCG level was identified as an independent predictor of treatment success among patients receiving Methotrexate for ectopic pregnancy
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในมหาราชนครศรีธรรมราชเวชสาร ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใด ๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในมหาราชนครศรีธรรมราชเวชสาร ถือเป็นลิขสิทธิ์ของมหาราชนครศรีธรรมราชเวชสาร หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใด จะต้องได้รับอนุญาตเป็นลายลักษณ์อักษรจากวารสารมหาราชนครศรีธรรมราชเวชสาร ก่อนเท่านั้น
