Development of Autoverification System for Complete Blood Count (CBC) Analysis of Patient in Thalang Hospital

Abstract

Background: Complete blood count (CBC) is a routine hematology test that plays a central role in clinical diagnosis and treatment monitoring. At Thalang Hospital, over 3,000 CBC tests are performed monthly, creating heavy workload and delays in reporting. Autoverification has been proposed as a strategy to improve efficiency and shorten turnaround time (TAT).

Objective: To develop and implement an autoverification system for CBC testing and to assess its impact on accuracy, TAT, reporting timeliness, medical technologist workload and cost.

Material and Methods: CBC results generated by the Mindray BC-6000 analyzer were processed using autoverification rules adapted from ISLH and CLIA 2025 guidelines. Manual blood smear reviews by three medical technologists served as the reference standard. Laboratory performance was compared before and after system implementation.

Results: The autoverification system verified 29.83% of CBC results. False-positive rates were 2.00% for RBC morphology, while most false negatives involved WBC and platelet counts. Mean TAT decreased from 21.95 to 7.60 minutes. The proportion of reports released within the target timeframe increased from 95.94% to 99.61%. Cost for manual smear review was reduced by 32.68% within three months.

Conclusion: The autoverification system significantly improved laboratory efficiency, reduced TAT, lessened staff workload and cost. Further refinement of verification rules is warranted to optimize accuracy and ensure sustainable application in routine practice.