The Relationship Between Gestational Hypertension and The Results of The Quadruple Test at Thungsong Hospital, Nakhon Si Thammarat Province
Keywords:
gestational hypertension, pre-eclampsia,, quadruple testAbstract
Background: Currently, pregnant women in Thailand are screened for Down syndrome using the quadruple biochemical test to identify high-risk cases (HRQT). Other Studies have suggested a possible association between HRQT and the development of hypertension in pregnancy. This study aims to investigate the relationship between HRQT and hypertensive disorders during pregnancy.
Objective: To evaluate the association between hypertension in pregnancy and the results of Down syndrome screening via the quadruple test at Thungsong Hospital, Nakhon Si Thammarat Province.
Materials and Methods: A retrospective cohort study based on medical records with positive quadruple test results from October 1, 2020 to September 30, 2023 using descriptive statistics to determine the correlation in data analysis.
Results: The study population consisted of 2,530 pregnant women. 167 women (6.6%) were classified as high-risk (HRQT) based on the Quadruple Test results. From confirmatory amniocentesis in the HRQT group, 3 fetuses were diagnosed with Down syndrome, and all 3 pregnancies were terminated. This left 164 HRQT cases who continued their pregnancies. Among them, gestational hypertension (GHT) was detected in 8.54% of the HRQT group (P < 0.05), compared to 0.85% in the LRQT group. Pre-eclampsia was found in 4.62% of the HRQT group (P < 0.05), compared to 0.68% in the LRQT group.
Conclusion: Pregnant women with high-risk results from the quadruple test for Down syndrome showed a statistically significant higher incidence of gestational hypertension and pre-eclampsia.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในมหาราชนครศรีธรรมราชเวชสาร ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใด ๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในมหาราชนครศรีธรรมราชเวชสาร ถือเป็นลิขสิทธิ์ของมหาราชนครศรีธรรมราชเวชสาร หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใด จะต้องได้รับอนุญาตเป็นลายลักษณ์อักษรจากวารสารมหาราชนครศรีธรรมราชเวชสาร ก่อนเท่านั้น
