Factors Affecting Chronic Kidney Disease and Mortality in Patients with Acute Kidney Injury Requiring Dialysis in Thungsong Hospital (Retrospective Study)
Keywords:
Acute kidney injury, Renal replacement therapy, Chronic kidney disease, MortalityAbstract
Background: Acute kidney injury (AKI) is a common clinical problem in critically ill patients and is associated with increased mortality. This retrospective study was conducted to determine the risk factors for chronic kidney disease (CKD) and mortality in patients with AKI requiring hemodialysis.
Objectives: To study the factors affecting chronic kidney disease and mortality in patients who have acute kidney injury and need renal replacement therapy in Thungsong Hospital
Material and Methods: Clinical data were collected from medical records of AKI patients requiring hemodialysis from July 2016 to July 2021 and were followed up at 3 months.
Results: Of the 161 patients with mean age 59.06±15.72 years were identified to have AKI requiring hemodialysis. Mortality and longterm renal replacement therapy rate among patients with AKI were 46 patients (28.6%) and 52 patients (32%), respectively. Among AKI patients on dialysis, the presence of advanced aged (adjusted OR, 1.04; 95%CI 1.01 to 1.08), infection (adjusted OR, 1.45; 95%CI, 1.58 to 3.630, inotrope use (adjusted OR, 2.27; 95%CI, 2.66 to 7.82) and high co-morbidity (adjusted OR, 3.21; 95%CI, 2.12 to 3.56) were found to be independent predictors of death. The independent predictors of CKD were baseline serum creatinine (adjusted OR, 2.24; 95%CI, 1.11 to 4.53), anemia (adjusted OR, 1.36; 95%CI, 1.45 to 4.09) and small kidney size (adjusted OR, 1.13; 95%CI, 1.34 to 3.73).
Conclusions: The study indicates the mortality rate among patients with AKI on dialysis was 28 percent. Advanced aged, systemic infection, inotrope use and high co-morbidity significantly associated with death among patients with AKI.
Keyword: Acute kidney injury, Renal replacement therapy, Chronic kidney disease, Mortality
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในมหาราชนครศรีธรรมราชเวชสาร ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใด ๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในมหาราชนครศรีธรรมราชเวชสาร ถือเป็นลิขสิทธิ์ของมหาราชนครศรีธรรมราชเวชสาร หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใด จะต้องได้รับอนุญาตเป็นลายลักษณ์อักษรจากวารสารมหาราชนครศรีธรรมราชเวชสาร ก่อนเท่านั้น
