Microbiological Data of Bloodstream Infection in Patients with Febrile Neutropenia in Maharaj Nakhon Si Thammarat Hospital.
Keywords:
febrile neutropenia, microbiological data, septicemiaAbstract
Background: Febrile neutropenia is a common condition and contributing to mortality in cancer patients who received chemotherapy. The choice of empiric antimicrobial regimen is based on susceptibility pattern of locally prevalent pathogens.
Objective: To determine the microbiological profile of bloodstream infection and antimicrobial susceptibility pattern of patients with febrile neutropenia in Maharaj Nakhon Si Thammarat Hospital.
Materials and Methods: A retrospective chart review of patients diagnosed with febrile neutropenia between January 2020 – June 2022atMaharajNakhon Si Thammarat Hospital was conducted to identify pathogen and antimicrobial susceptibility.
Results: There were 133 febrile neutropenia episodes in 79 patients. The overall blood culture positive was 22%. The most common organisms isolated were gram negative bacilli (86.2% of bacteremia), includeE. coli (5%), K.pneumoniae. (4.5%) and P.aeruginosa (4.5%). All of pathogens were non-drug resistance. Gram positive bacteria were 4 episodes (13.8% of bacteremia), 1 episode was methicillin-resistant coagulase-negative staphylococci (MRCoNs). Fungal infection were 13 episodes (10%). Aspergillusspp. And Candida spp. were 7.5% and 2.3% respectively. The median length of stay was 10 days. The overall mortality rate was 10.5%.
Conclusions: The common pathogens isolated from patients with febrile neutropenia at Maharaj Nakhon Si Thammarat hospital were gram negative bacilli. Most of them were non-drug resistance pathogens. Empirical antibiotic regimen can be used based on susceptibility pattern.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในมหาราชนครศรีธรรมราชเวชสาร ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใด ๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในมหาราชนครศรีธรรมราชเวชสาร ถือเป็นลิขสิทธิ์ของมหาราชนครศรีธรรมราชเวชสาร หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใด จะต้องได้รับอนุญาตเป็นลายลักษณ์อักษรจากวารสารมหาราชนครศรีธรรมราชเวชสาร ก่อนเท่านั้น
