Results of Treatment of Patients with Osteoarthritis Knee With Platlets-rich Plasma Intra-articular Injection Nakhon Sri Thammarat

Authors

  • Pranpawee Rojcharoenngam Department of Orthopedic Surgery. MaharajNakhon Si Thammarat Hospital.

Keywords:

plasma-rich platlets, Osteoarthritis knee

Abstract

Background: Knee osteoarthritis is the most common cause of disability in the elderly in Thailand, and most common disease of orthopaedic outpatient case at Maharaj Nakhon Si Thammarat Hospital. Intraarticular platelet-rich plasma (PRP) injection at the site of a cartilage lesion is the natural treatment for the knee cartilage repair.Using the serum components or the patient's own cells, there is no allergic problem, andno additional expenses in every medical eligibility fund.This is anoption for the patient with moderate osteoarthritis patients with an oxford score greater than 9 and no knee deformity.

Objective: Forstudy results of treatment of patients with osteoarthritis knee with platlets-rich plasma intra-articular injection.

Material and Methods: Patients with moderate primary osteoarthritis was enrolled, who has an oxford score greater than 9, and no knee deformity.Injecting platlets-rich plasma (PRP) that prepared from the patient's own blood into two needles, each needle 1 month apart.Follow up on treatment results after 2 injections at 1 week, 3 weeks, 3 months, and 6 months.Theresults were assessed by the Thai version of the Modified WOMAC questionnaire.

Results: Patient with osteoarthritis sknee receives platlets rich plasma (PRP): 21 patients, aged 40-70, mean age 65.5,6 males (28.57%), 15 females (71.43%). Body mass index (BMI) ranged from 28.3 - 37.5, mean 30.03.The WOMAC score before treatment was a mean 67.9 ± 7.3. After 2 dose of injections, the WOMAC score was found to be significantly lower at P-values ​​<0.001, both after injection for 1 week and 1 month (67.1 ± 7.9 vs. 43.8 ± 8.2), 1 week and 3 months (67.1 ± 7.9. With 34.8 ± 6.9), 1 week and 6 months (67.1 ± 7.9 with 38.7 ± 6.6), 1 month and 3 months (43.8 ± 8.2 with 34.8 ± 6.9), 1 month and 6 months (43.8 ± 8.2 with 38.7 ± 6.6).Except for 3 months and 6 months (34.8 ± 6.9 and 38.7 ± 6.6) P-values ​​= 0.003.

Conclusions :Injection of platlets-rich plasma(PRP) in primary osteoarthritis knee patients with an oxford score greater than 9 and radiographic probe angle of less than 10 degrees, was a very effective treatment for the first 3 months and Get good results over a period of up to 6 months.

References

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Published

2022-01-01

How to Cite

1.
Rojcharoenngam P. Results of Treatment of Patients with Osteoarthritis Knee With Platlets-rich Plasma Intra-articular Injection Nakhon Sri Thammarat. MNST Med J [internet]. 2022 Jan. 1 [cited 2026 Jan. 4];5(2):13-20. available from: https://he01.tci-thaijo.org/index.php/MNSTMedJ/article/view/253962

Issue

Vol. 5 No. 2 (2022): January 2022 - June 2022

Section

Original Article

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