Health–Related Quality of Life in Treated Oral Cancer Patients
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Abstract
Previous studies revealed that oral cancer survivors could still have significant loss of oral functions as well as having social and psychological issues after cancer treatment. This study aimed 1) to investigate the Health–Related Quality of Life (HRQOL) in oral cancer patients after surgical treatment 2) for comparing the HRQOL in physical aspect with socio–emotional aspect and 3) to investigate factors related to HRQOL. This study was conducted using the Thai version of University of Washington’s Quality of Life Questionnaire (UW–QOL), version 4 with 80 histologically confirmed oral squamous cell carcinoma (OSCC) patients who were treated at the Faculty of Dentistry, Khon Kaen University, Thailand. T–stage, neck dissection, treatment modality, and type of reconstruction were the predictive factors of patient’s physical function (p<0.05). Interestingly, the post–treatment overall QOL of the patients was “good” (62±13.0) with the HRQOL score in socio–emotional (87.86±22.29) significantly higher than physical function (79.96±27.42) (p<0.001). Therefore, to improve post–treatment physical function, active surveillance, such as oral cancer screening in high–risk populations, and good health education regarding self–detection of early oral malignant lesion, should be implemented for early diagnosis and prompt medical treatments. Also, health care providers may need to emphasize on preserving the oral functions and facial appearance as much as possible.
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บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการลงตีพิมพ์ในวิทยาสารทันตแพทยศาสตร์ มหาวิทยาลัยขอนแก่นถือเป็นลิขสิทธิ์เฉพาะของคณะทันตแพทยศาสตร์ มหาวิทยาลัยขอนแก่น หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใด ๆ จะต้องได้รับอนุญาตเป็นลายลักษณ์อักษร จากคณะทันตแพทยศาสตร์ มหาวิทยาลัยขอนแก่นก่อนเท่านั้น
References
Salian V, Dinakar C, Shetty P, Ajila V. Etiological trends in oral squamous cell carcinoma: A retrospective institutional study. Cancer Transl Med 2016;2(2):33.
Information Technology Division National Cancer Institute. Hospital Based Cancer Registry 2018. New Thammada Press (Thailand); 2019.
Shah JP, Patel SG, Singh B, Wong RJ. Jatin Shah’s Head and neck surgery and oncology. Elsevier Health Sciences;2020.
Soares JRN, Dias FL, Lima RRM de A, Toscano UB, Pontes ACP, Botinelly RD, et al. Assessment of quality of life in patients with advanced oral cancer who underwent mandibulectomy with or without bone reconstruction. Rev Assoc MÃcopyrightdica Bras [Internet]. 2018;64:710–6. Available from: http:// www.scielo.br/scielo.php?script=sci_arttext&pid=S0104–42302018000800710&nrm=iso
Dzebo S, Mahmutovic J, Erkocevic H. Quality of life of patients with oral cavity cancer. Mater Socio–Medica [Internet]. 2017 Mar;29(1):30–4. Available from: https://pubmed.ncbi.nlm.nih.gov/28484351
Kuysakorn P, Bhalang K, Piboonratanakit P. Evaluation of health–related quality of life in a group of Thai oral cancer patients [Internet]. Chulalongkorn university; 2009. Available from: http://cuir.car.chula.ac.th/ handle/123456789/16056
Abbas S, Syed MUUT, Raheem A, Saeed J, Hashmi SS, Karim M, et al. Assessment of factors affecting quality of life in oral squamous cell carcinoma patients using university of washington quality of life questionnaire. Cureus. 2019;11(1). e3904. doi: 10.7759/cureus.3904.
Murphy BA, Ridner S, Wells N, Dietrich M. Quality of life research in head and neck cancer: a review of the current state of the science. Crit Rev Oncol Hematol 2007;62(3):251–67.
Rogers SN, Lowe D, Brown JS, Vaughan ED. A comparison between the University of Washington head and neck disease–specific measure and the medical short form 36, EORTC QOQ–C33 and EORTC head and neck 35. Oral Oncol 1998;34(5):361–72.
Meier JK, Schuderer JG, Zeman F, Klingelhöffer C, Hullmann M, Spanier G, et al. Health–related quality of life: A retrospective study on local vs. microvascular reconstruction in patients with oral cancer. BMC Oral Health 2019;19(1):62.
Lowe D, Rogers SN. University of Washington quality of life questionnaire (UW–QOL v4). Pain 2012;545(6): 31–107.
Amin MB, Edge SB. AJCC Cancer Staging Manual 8th Ed. Springer; 2017.
Rogers SN. Improving quality–of–life questionnaires in head and neck cancer. Expert Rev Qual Life Cancer Care 2016;1(1):61–71.
Rogers S, Ahad SA, Murphy AP. A structured review and theme analysis of papers published on ‘quality of life’in head and neck cancer: 2000–2005. Oral Oncol 2007;43(9):843–68.
Ojo B, Genden EM, Teng MS, Milbury K, Misiukiewicz KJ, Badr H. A systematic review of head and neck cancer quality of life assessment instruments. Oral Oncol 2012;48(10):923–37.
Kanatas AN, Rogers SN. A national survey of health–related quality of life questionnaires in head and neck oncology. Ann R Coll Surg Engl [Internet]. 2004 Jan;86(1):6–10. Available from: https://pubmed. ncbi.nlm.nih.gov/15005937
Kanatas AN, Mehanna HM, Lowe D, Rogers SN. A second national survey of health–related quality of life questionnaires in head and neck oncology. Ann R Coll Surg Engl 2009;91(5):420–5.
Iamaroon A, Pattanaporn K, Pongsiriwet S, Wanachantararak S, Prapayasatok S, Jittidecharaks S, et al. Analysis of 587 cases of oral squamous cell carcinoma in northern Thailand with a focus on young people. Int J Oral Maxillofac Surg [Internet]. 2004 Feb 1;33(1):84–8. Available from: https://www.science direct.com/science/article/pii/S0901502703905030
Loeffelbein D, Ritschl LM, Güll FD, Roth M, Wolff KD, Mücke T. Influence of possible predictor variables on the outcome of primary oral squamous cell carcinoma: A retrospective study of 392 consecutive cases at a single centre. Int J Oral Maxillofac Surg [Internet]. 2017 Apr 1 [cited 2021 Apr 10];46(4):413–21. Available from: https://doi.org/10.1016/j.ijom. 2016.11.014
Pierre CS, Dassonville O, Chamorey E, Poissonnet G, Ettaiche M, Santini J, et al. Long–term quality of life and its predictive factors after oncologic surgery and microvascular reconstruction in patients with oral or oropharyngeal cancer. Eur Arch Otorhinolaryngol 2014;271(4):801–7.
Tschudi D, Stoeckli S, Schmid S. Quality of life after different treatment modalities for carcinoma of the oropharynx. The Laryngoscope 2003;113(11):1949–54.
Bhanja A, Dsouza D, Roy C, Poddar R. Assessment of quality of life in oral cancer patients following pectoralis major myocutaneous flap reconstruction. Int J Contemp Med Res 2016;1(3):1366–71.
Schliephake H, Jamil MU. Prospective evaluation of quality of life after oncologic surgery for oral cancer. Int J Oral Maxillofac Surg [Internet]. 2002 Aug 1 [cited 2021 Feb 6];31(4):427–33. Available from: https:// doi.org/10.1054/ijom.2001.0194
Borggreven PA, Aaronson NK, Verdonck–de Leeuw IM, Muller MJ, Heiligers MLCH, Bree R de, et al. Quality of life after surgical treatment for oral and oropharyngeal cancer: A prospective longitudinal assessment of patients reconstructed by a microvascular flap. Oral Oncol [Internet]. 2007 Nov 1;43(10):1034–42. Available from: https://www.sciencedirect.com/ science/article/pii/S1368837506003137
Rogers SN, Lowe D, Brown JS, Vaughan ED. The University of Washington head and neck cancer measure as a predictor of outcome following primary surgery for oral cancer. Head Neck [Internet]. 1999 Aug 1 [cited 2021 Feb 6];21(5):394–401. Available from: https://doi.org/10.1002/(SICI)1097–0347(199908)21:5 <394::AID–HED3>3.0.CO;2–Q
Crowder SL, Najam N, Sarma KP, Fiese BH, Arthur AE. Quality of life, coping strategies, and supportive care needs in head and neck cancer survivors: a qualitative study. Support Care Cancer [Internet]. 2021 Aug 1;29(8):4349–56. Available from: https://doi.org/ 10.1007/s00520–020–05981–1