Effects of Matrix Metalloproteinase Inhibitors on the Shear Bond Strength of Resin Composite to Dentin when Using a Universal Adhesive in Etch & Rinse Mode

Main Article Content

Eaknarin Jiewchaisak
Pavinee Padipatvuthikul Didron

Abstract

The aim of this study was to investigate shear bond strength between resin composite and dentin using 2 MMP inhibitors and a universal adhesive in etch and rinse mode. Twenty extracted human premolars were prepared and cut in the mesio-distal direction. Thirty-nine dentin samples were embedded in acrylic blocks. The samples were divided into 3 groups (n=13 each) depending on the pretreated condition; pretreatment with either 2% chlorhexidine or 2% doxycycline and no dentin pretreatment (control). All groups were then applied with a universal adhesive in etch and rinse mode. The mean shear bond strength (SBS) of the 2% doxycycline pretreated was significantly higher (20.77 MPa) compared with the control group (16.91 MPa) (P<0.05)

Article Details

How to Cite
1.
Jiewchaisak E, Padipatvuthikul Didron P. Effects of Matrix Metalloproteinase Inhibitors on the Shear Bond Strength of Resin Composite to Dentin when Using a Universal Adhesive in Etch & Rinse Mode. Khon Kaen Dent J [Internet]. 2022 Mar. 16 [cited 2024 Apr. 26];25(1):42-51. Available from: https://he01.tci-thaijo.org/index.php/KDJ/article/view/248977
Section
Research Articles
Share |

References

Buonocore M. A simple method of increasing the adhesion of acrylic filling materials to enamel surfaces. J Den Res 1955;34:849-53.

Sofan E, Sofan A, Palaia G, Tenore G, Romeo U, Migliau G. Classification review of dental adhesive systems: from the IV generation to the universal type. Annali di stomatologia 2017;8(1):1.

Frankenberger R, Tay FR. Self-etch vs etch-and-rinse adhesives: effect of thermo-mechanical fatigue loading on marginal quality of bonded resin composite restorations. Dent Mater 2005;21(5):397-412.

Hanabusa M, Mine A, Kuboki T, Momoi Y, Van Ende A, Van Meerbeek B, et al. Bonding effectiveness of a new 'multi-mode' adhesive to enamel and dentine. J Dent 2012;40(6):475-84.

Marchesi G, Frassetto A, Mazzoni A, Apolonio F, Diolosà M, Cadenaro M, et al. Adhesive performance of a multi-mode adhesive system: 1-year in vitro study. J Dent 2014;42(5):603-12.

Tuncer D, Yazici A, Özgünaltay G, Dayangac B. Clinical evaluation of different adhesives used in the restoration of non-carious cervical lesions: 24-month results. Aust Dent J 2013;58(1):94-100.

Thanaratikul B, Santiwong B, Harnirattisai C. Microshear Bond Strength of a Universal Adhesive to Primary Dentin 34th The National Graduate Research Conference 2015;34:1233-39.

Pashley DH. The effects of acid etching on the pulpodentin complex. Oper Dent 1992;17(6):229-42.

Sulkala M. Matrix Metalloproteinase (MMPs) in the dentin-pulpcomplex of healthy and carious teeth. OULU 2004:1-61.

Komori P, Pashley DH, Tjäderhane L, Breschi L, Mazzoni A, de Goes M. Effect of 2%chlorhexidine digluconate on the bond strength to normal versus caries-affected dentin. Oper Dent 2009;34(2):1565-71.

Perdigão J, Reis A, Loguercio DA. Dentin adhesion and MMPs: a comprehensive review. J Esthet Restor Dent 2013;25(4):219-41.

Tezvergil-Mutluay A, Agree K, Hoshika T, Tay F, Pashley D. The inhibitory effect of polyvinylphosphonic acid on functional matrix metalloproteinase activities in human demineralized dentin. Acta Biomater 2010;6(10): 4136-42.

Palasuk J, Windsor L, Platt J, Lvov Y, Geraldeli S, Bottino M. Doxycycline-loaded nanotube-modified adhesives inhibit MMP in a dose-dependent fashion. Clin Oral Investig 2018;22(3):1243-52.

Stanislawczuk R, Costa JAD, Polli LG, Reis A, Loguercio AD. Effect of tetracycline on the bond performance of etch-and-rinse adhesives to dentin. Braz Oral Res 2011;25(5):459-65.

Prabhu S, Joseph V, John M, Babu A, Chand C, Ajas A. Effect of 2% Chlorhexidine on the Bond Strength of Direct Composite Restoration to Dentin: An invitro Study. Int J Prev and Clin Dent Res 2006;3(3):187-91.

Heshmat H, Jahangiri M, Ganjkar M, Arjomand M, Kharazifard M. Effect of Chlorhexidine on Micro-Shear Bond Strength of Two Adhesive Systems After Aging. JIDAI 2018;30(1):9-14.

Pei Z, Hui Z. Evaluate the effect of different mmps inhibitors on adhesive physical properties of dental adhesives, bond strength and mmp substarte activity. Sci Rep 2017;7(1):1-11.

Montagner AF, Sarkis-Onofre R, Pereira-Cenci, Cenci MS. MMP inhibitors on dentin stability. J Dent Res 2014;93(8):733-43.

Sirisha K, Rambabu T, Shankar Y, Ravikumar P. Validity of bond strength tests: A critical review: Part I. (Review Article). J Conserv Dent 2014;17(4):305-11.

Niu L, Zhang W, Pashley D, Breschi L, Mao J, Chen J. biomimetic remineralization of dentin. Dent Mater 2014;30(1):1-35.

Benjamin M, Khalil R. Matrix Metalloproteinase inhibitors as investigative tools in the pathogenesis and management of vascular disease. EXS 2012;103:209-79.

Deniz C, Tulga F, Baris K, Inci B, Ozlem I. Adhesion to primary and permanent dentin and a simple model approach. Eur J Dent 2009;3(1):32-41.