Effects of Matrix Metalloproteinase Inhibitors on the Shear Bond Strength of Resin Composite to Dentin when Using a Universal Adhesive in Etch & Rinse Mode
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Abstract
The aim of this study was to investigate shear bond strength between resin composite and dentin using 2 MMP inhibitors and a universal adhesive in etch and rinse mode. Twenty extracted human premolars were prepared and cut in the mesio-distal direction. Thirty-nine dentin samples were embedded in acrylic blocks. The samples were divided into 3 groups (n=13 each) depending on the pretreated condition; pretreatment with either 2% chlorhexidine or 2% doxycycline and no dentin pretreatment (control). All groups were then applied with a universal adhesive in etch and rinse mode. The mean shear bond strength (SBS) of the 2% doxycycline pretreated was significantly higher (20.77 MPa) compared with the control group (16.91 MPa) (P<0.05)
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