Prevalence and Risk Factors of High-Level Oral Microbe among Dental Patients
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Abstract
The composition of oral microbiota is associated with a health status of the host. However, the shifting of microbiome is related to various factors. We statistically examined a possible correlation between the risk factors and the amount of three selected types of oral microbes that are important to oral diseases (Streptococcus mutans, Lactobacilli and Candida) using the cross-sectional study method and multiple logistic regression analysis. A total of 258 subjects who live in the urban area (Bangkok) and three randomly selected rural areas (Ratchaburi, Nakhon Nayok and Sukhothai) were recruited to this study in January to July 2015. The results showed that participants with the high level of S. mutans (>105 CFU/ml) are more likely to 1) live in the urban area than in the rural one by a factor of 14.73 (95% CI=2.65-82.00), 2) have secondary education than primary or no education by a factor of 5.26 (95% CI=1.41 -19.67), and 3) have hyposalivation than normal salivary flow rate by a factor of 23 (95% CI=4.15 -127.36). In addition, participants who lost one more tooth have higher risk of having the high level of S. mutans than those losing less teeth by a factor of 1.08 (95% CI=1.003-1.17). In the case of high level of Lactobacilli (>105 CFU/ml), participants with hyposalivation have higher risk than those with normal salivary flow rate by a factor of 7.67 (95% CI=1.89-31.21), while having one more tooth loss increases the risk by a factor of 1.08 (95% CI=1.02-1.13). Moreover, losing one more tooth increases the risk of having the high level of Candida (>104 CFU/ml) by a factor of 1.07 (95% CI=1.01-1.12) when the hyposalivation and underlying health conditions have been controlled. This result might be able to be used as a guideline to examine the risk factors of having high levels of oral microbes in the future.
Article Details
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการลงตีพิมพ์ในวิทยาสารทันตแพทยศาสตร์ มหาวิทยาลัยขอนแก่นถือเป็นลิขสิทธิ์เฉพาะของคณะทันตแพทยศาสตร์ มหาวิทยาลัยขอนแก่น หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใด ๆ จะต้องได้รับอนุญาตเป็นลายลักษณ์อักษร จากคณะทันตแพทยศาสตร์ มหาวิทยาลัยขอนแก่นก่อนเท่านั้น
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