Dental Management for Alagille Syndrome: A Case Report

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Published: Jun 27, 2019
Keywords:
Alagille syndrome Dental management Oral manifestations

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Onauma Angwaravong
Department of Preventive Dentistry, Faculty of Dentistry, Khon Kaen University, Amphur Muang, Khon Kaen
Rutchada Kittiprawong
Dental Department, Thabo Crown Prince Hospital, Amphur Thabo, Nong Khai.
Thidarat Angwarawong
Department of Prosthodontics, Faculty of Dentistry, Khon Kaen University, Amphur Muang, Khon Kaen.

Abstract

Alagille syndrome is a complex genetic disorders, having high variability in severity and multi-organ system involvement, with the presence of at least three out of five major systems: liver, heart, skeletal, eye, face, and some other organs may be involved. A multidisciplinary approach is needed to manage Alagille syndrome. Dental management for patient with Alagille syndrome could be different from healthy patients due to multi-organ disorders especially the impairments of liver function and congenital heart defects. Up to date, there are few articles addressing dental management for patients with Alagille syndrome. Thus, this article aims to review literatures related to Alagille syndrome regarding the etiology, incidence, clinical features, diagnosis, treatment, and dental management with case report.

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How to Cite
1.
Angwaravong O, Kittiprawong R, Angwarawong T. Dental Management for Alagille Syndrome: A Case Report. Khon Kaen Dent J [Internet]. 2019 Jun. 27 [cited 2024 Nov. 20];22(1):69-80. Available from: https://he01.tci-thaijo.org/index.php/KDJ/article/view/198593
Issue
Vol. 22 No. 1 (2019)
Section
Clinical Science

บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการลงตีพิมพ์ในวิทยาสารทันตแพทยศาสตร์ มหาวิทยาลัยขอนแก่นถือเป็นลิขสิทธิ์เฉพาะของคณะทันตแพทยศาสตร์ มหาวิทยาลัยขอนแก่น หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใด ๆ จะต้องได้รับอนุญาตเป็นลายลักษณ์อักษร จากคณะทันตแพทยศาสตร์ มหาวิทยาลัยขอนแก่นก่อนเท่านั้น

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References

Berniczei-Royko A, Chalas R, Mitura I, Nagy K, Prussak E. Medical and dental management of Alagille syndrome:a review. Med Sci Monit 2014;20:476-80.

Alagille D, Odièvre M, Gautier M, Dommergues JP. Hepatic ductular hypoplasia associated with characteristic facies, vertebral malformations, retarded physical, mental, and sexual development, and cardiac murmur. J Pediatr 1975;86(1):63-71.

Grochowski CM, Loomes KM, Spinner NB. Jagged1 (JAG1):Structure, expression, and disease associations. Gene 2016;576(1 Pt 3):381-4.

Li L, Krantz ID, Deng Y, Genin A, Banta AB, Collins CC et al. Alagille syndrome is caused by mutations in human Jagged1,which encodes a ligand for Notch1. Nat Genet 1997;16(3):243-51.

Spinner NB, Leonard LD, Krantz ID, Adam MP, Ardinger HH, Pagon RA, et al. Alagille Syndrome. GeneReviews® [Internet].1993-2018 [cited 2018 Jan 31]. Available from:https://www.ncbi.nlm.nih.gov/books/NBK1273/.

Mc Daniell R, Warthen DM, Sanchez-Lara PA, Pai A, Krantz ID, Piccoli DA, et al. NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway. Am J Hum Genet 2006;79(1):169-73.

Kamath B, Bason L, Piccoli D, Krantz I, Spinner N. Consequences of JAG1 mutations. J Med Genet 2003;40(12):891-95.

Kamath BM, Loomes KM, Piccoli DA. Medical management of Alagille syndrome. J Pediatr Gastroenterol Nutr 2010;50(6):580-86.

Cho JM, Oh SH, Kim HJ, Kim JS, Kim KM, Kim GH, et al. Clinical features, outcomes, and genetic analysis in Korean children with Alagille syndrome. Pediatr Int 2015;57(4):552-7.

Saleh M, Kamath BM, Chitayat D. Alagille syndrome: clinical perspectives. Appl Clin Genet 2016;9:75-82.

Turnpenny PD, Ellard S. Alagille syndrome: pathogenesis, diagnosis and management. Eur J Hum Genet 2012;20(3):251-7.

Emerick KM, Rand EB, Goldmuntz E, Krantz ID, Spinner NB, Piccoli DA. Features of Alagille syndrome in 92 patients: frequency and relation to prognosis. Hepatology 1999;29(3):822-9.

Mc Elhinney DB, Krantz ID, Bason L, Piccoli DA, Emerick KM, Spinner NB, et al. Analysis of cardiovascular phenotype and genotype-phenotype correlation in individuals with a JAG1 mutation and/or Alagille syndrome. Circulation 2002;106(20):2567-74.

Sanderson E, Newman V, Haigh SF, Baker A, Sidhu PS. Vertebral anomalies in children with Alagille syndrome: an analysis of 50 consecutive patients. Pediatr Radiol 2002;32(2):114-19.

Olsen IE, Ittenbach RF, Rovner AJ, Leonard MB, Mulberg AE, Stallings VA, et al. Deficits in size-adjusted bone mass in children with Alagille syndrome. J Pediatr Gastroenterol Nutr 2005;40(1):76-82.

Lykavieris P, Crosnier C, Trichet C, Meunier-Rotival M, Hadchouel M. Bleeding tendency in children with Alagille syndrome. Pediatrics 2003;111(1):167-70.

Kamath BM, Spinner NB, Emerick KM, Chudley AE, Booth C, Piccoli DA, et al. Vascular anomalies in Alagille syndrome: a significant cause of morbidity and mortality. Circulation 2004;109(11):1354-8.

Al-Mutawa S, Mathews B, Salako N. Oral findings in Alagille syndrome. A case report. Med Princ Pract 2002;11(3):161-3.

Chatterjee M, Mason C. Talon cusps presenting in a child with Alagille’s syndrome--a case report. J Clin Pediatr Dent 2007;32(1):61-3.

Golla K, Epstein JB, Cabay RJ. Liver disease: current perspectives on medical and dental management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;98(5):516-21.

Brewer A, Correa ME. Guidelines for dental treatment of patients with inherited bleeding disorders. Haemophilia 2005;11:504-9.

Douglas LR, Douglass JB, Sieck JO, Smith PJ. Oral management of the patient with end-stage liver disease and the liver transplant patient. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998;86(1):55-64.

Amarapurkar DN. Prescribing Medications in Patients with Decompensated Liver Cirrhosis. Int J Hepato 2011;2011.

Cruz-Pamplona M, Margaix-Muñoz M, Pérez MG. Dental considerations in patients with liver disease; 2011.

Wilson W, Taubert KA, Gewitz M, Lockhart PB, Baddour LM, Levison M, et al. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation 2007;116(15):1736-54.

Bales CB, Kamath BM, Munoz PS, et al. Pathologic lower extremity fractures in children with Alagille syndrome. J Pediatr Gastroenterol Nutr 2010;51(1):66-70.

Wright GZ, Kupietzky A. Behavior management in dentistry for children: John Wiley & Sons;2014.

Bureau of Nutrition, Department of Health, Ministry of Public Health. Growth chart [Internet]. 2014 [cited 2018 Jan 31]. Available from:https://nutrition.anamai.moph.go.th/images/file/2- 7_boyart-web.gif.

Greene JG, Vermillion JR. The simplified oral hygiene index. The J Am Den Assoc 1964;68(1):7-13.

Dentistry AAoP. Guideline on caries-risk assessment and management for infants, children, and adolescents. Pediatric dentistry 2013;35(5):E157.

Abdullah WA, Khalil H. Dental extraction in patients on warfarin treatment. Clin Cosmet Investig Dent 2014;6:65-9.

The Dental council of thailand. Dental safety Goal & Guideline 2015[Internet]. 2015[cited 2018 Aug 23]. Available from:https://www.dentalcouncil.or.th/th/dental_safety_goal.php.

The Dental association of Thailand. Guideline on Fluoride Therapy 2017 [Internet]. 2017 [cited 2018 Jan 31]. Available from: https://www.thaidental.net/web/.