• Charee JANSUPOM Sport and Health Sciences Program, Faculty of Science and Liberal Arts Rajamangala University of Technology Isan, Thailand
  • Kanarat DEFOSSEZ
  • Siripaisarn YIMPRASERT
  • Sawitree PAKKARATO
  • Pakpoom PHILUKE


Chronic kidney disease, Lift-build-line exercise, Muscle Strength, Cardiorespiratory Fitness, Lipid Profile


     This study was a quasi-experimental research. The purpose was to compare the effects of life-build-line exercise on muscle strength, cardiovascular endurance, and lipid profile. All the subjects were diagnosed by physicians as stage 3 chronic kidney disease patients, consisting of eight subjects and divided into two groups.: the life-build-line exercise group (LBL) (n = 4, age: 58.33±4.73 years; glomerular filtration rate; eGFR = 51.23±4.76 ml/min/1.73m2) and the callisthenic exercise group (n = 4, age: 61.75±2.75 years; glomerular filtration rate; eGFR = 54.05±4.13 ml/min/1.73m2) performed for 50 minutes, 3 days a week for 12 weeks. The results of the study of life-build-line exercise showed that the life-build-line exercise group had a greater improvement in forearm muscle strength on the left hand by hand grip strength test than the callisthenic exercise group, which was statistically significant (p<0.05). The cardiorespiratory endurance of the 6-minute walk test and the lipid profiles of the two groups were not different. But it was found that after 12 weeks of training, the life-build-line exercise group tended to have better leg muscle strength cardiovascular endurance and lipid profile than the callisthenic exercise group. These findings indicate that life-builds-line exercise is appropriate and can improve forearm muscle strength in patients with chronic kidney disease stage 3.

(Journal of Sports Science and Technology 2023; 23 23(2):20-32)
(Received: 1 May 2023, Revised: 8 July 2023, Accepted: 13 July 2023)

* Corresponding Author: Pakpoom PHILUKE
Sport and Exercise Sciences, Faculty of Science and Technology
Nakhon Ratchasima Rajabhat University, THAILAND
Email: [email protected]

Author Biography


Sport and Exercise Sciences, Faculty of Science and Technology,
Nakhon Ratchasima Rajabhat University, THAILAND


Andrew SL, Josef C, Ethan B, Annamaria TK, Adeera L, Michael WS, Ronald JH, Ronald DP, Joseph L, Garabed E. National kidney foundation practice guidelines for chronic kidney disease: Evaluation, Classification, and Stratification. Ann Intern Med 2003;15;139(2):137-47

Global burden of disease chronic kidney disease collaboration. Global, regional, and national burden of

chronic kidney disease, 1990-2017: a systematic analysis for the global burden of disease study 2017. Lancet 2020;29:709-33.

Roxana M, George D. Dangas, Steven D. Contrast associated acute kidney injury. N Engl J Med 2019;


Charles JF et al. Lipid management in patients with chronic kidney disease. Nat Rev Nephrol 2018;14: 727-49. 5. World Health Organization. Guidelines on physical activity and sedentary behavior. Br J Sports Med 2020; 54:1451–62.

Zhang QL, and Rothenbacher D. Prevalence of chronic kidney disease in population-base studies systemic review. BMC Public heath 2008;8(117):1-8.

Ali B and Gray-Vickrey P. Limiting the damage from acute kidney injury. Nursing, 2011;41(3):22-31.

Heiwe S and Jacobson SH. Exercise training in adults with CKD: A systematic review and meta-analysis. Am J Kidney Dis 2014;64:383-93.

Mallamaci F, Pisano A, Tripepi A. Hypertension management in chronic kidney disease. Nephrol Dial Transplant 2020;1–2.

Aoike DT, Baria F, Kamimura MA, Ammirati A, de Mello MT, Cuppari L. Impact of home-based aerobic exercise on the physical capacity of overweight patients with chronic kidney disease. Int Urol Nephrol 2015;47(2):359-67.

Baria F, Maria AK, Danilo TA, Adriano A, Mariana L Rocha, Marco Túlio de Mello, Lilian C. Randomized controlled trial to evaluate the impact of aerobic exercise on visceral fat in overweight chronic disease patients kidney. Nephrol Dial Transplant 2014;29:857–864.

Gomes, TS, Aoike DT, Baria F, Graciolli, FG, Moyses RM, Cuppari L. Effect of aerobic exercise on markers of bone metabolism of overweight and obese patients with chronic kidney disease. J. Ren. Nutr 2017,27: 364–71.

Barcellos FC, Del Vecchio FB, Reges A, Mielke, G, Santos IS, Umpierre D, Bohlke M, Hallal P. Exercise in patients with hypertension and chronic kidney disease: A randomized controlled trial. J. Hum. Hypertens 2018,32:397–407.

Hamada M, Yasuda Y, Kato S, Arafuka H, Goto M, Hayashi M, Kajita E, Maruyama S. The effectiveness and safety of modest exercise in Japanese patients with chronic kidney disease: A single-armed interventional study. Clin. Exp. Nephrol 2016,20:204–11.

Belik FS, Silva VR, Braga GP, Bazan R, Vogt BP, Caramori JCT et al. Influence of intradialytic aerobic training in cerebral blood flow and cognitive function in patients with chronic kidney disease: A pilot randomized controlled trial. Nephron 2018;140:9–17.

Panyaek N, Sirivong D, Konharn K, Tunkamnerdthai O, Aneknun P, Leelayuwat N. Exercise intensity and substrate utilization in healthy sedentary females using the Life-Build-Line device. J Med Assoc Thai 2017;100:318-25.

Mikesky AE, Robert T, Janet K.W, David MH, Jeffrey EE. Efficacy of a home-based training program for older adults using elastic tubing. Eur J Appl Physiol 1994;69:316-20.

Booth FW, Gordon SE, Carlson CJ et al. Waging war on modern chronic diseases: primary prevention through exercise biology. J Appl Physiol 2000;88:774–87.

Dickinson HO, Mason JM, Nicolson DJ et al. Lifestyle interventions to reduce raised blood pressure: a systematic review of randomized controlled trials. J Hypertens 2006;24:215–33.

Stewart KJ. Exercise training and the cardiovascular consequences of type 2 diabetes and hypertension: plausible mechanisms for improving cardiovascular health. JAMA 2002;288:1622–31.

Rossi AP, Burris DD, Lucas FL, Crocker GA, Wasserman JC. Efects of a renal rehabilitation exercise program in patients with CKD: a randomized controlled trial. Clin J Am Soc Nephrol 2014;9(12):2052–8

Hiraki K, Shibagaki Y, Izawa KP, Hotta C, Wakamiya A, Sakurada T, et al. Effects of home-based exercise on pre-dialysis chronic kidney disease patients: a randomized pilot and feasibility trial. BMC Nephrol 2017; 18(1): 1–7.

Hellberg M, Ho¨glund P, Svensson P et al. Randomized controlled trial of exercise in CKD-the RENEXC study. Kidney IntRep 2019;4:963–76.

Robert AW and Cynthia DB. Minimal Clinically Important Differences in the Six-Minute Walk Test and the Incremental Shuttle Walking Test. Journal of Chronic Obstructive Pulmonary Disease 2005;2(1):125-9.

Danilo TA. Impact of home-based aerobic exercise on the physical capacity of overweight patients with chronic kidney disease. Int Urol Nephrol 2015;47(2):359-67.

Sharlene AG, Pelagia K, Thomas HM, Helen LM, Robert R, Herolin L, et al. Effect of exercise training on estimated GFR, vascular health, and cardiorespiratory fitness in patients with CKD: a pilot randomized controlled trial. Am J Kidney Dis 2015;65:425-34.

Dumortier M, Brandou F, Perez-Martin A, Fedou C, Mercier J, Brun JF. Low intensity endurance exercise

targeted for lipid oxidation improves body composition and insulin sensitivity in patients with the metabolic syndrome. Diabetes Metab 2003;29:509-18.

National Kidney Foundation. KDOQI Clinical Practice Guideline for Diabetes and CKD. Am J Kidney Dis. 2012;60(5):850-86.






Original article