Prevalence of carbapenem resistant Acinetobacter baumannii complex in Mae Sot Hospital, Tak Province
Keywords:
Acinetobacter baumannii complex, Carbapenem, CarbAcineto NP test, Carbapenemase enzymeAbstract
Acinetobacter baumannii complex is a significant cause of hospital-acquired infectionsand is often resistant to multiple antimicrobial agents, particularly carbapenems. The most common resistance mechanism is the production of carbapenemases that inactivate the drug. This study aimed to determine the prevalence of carbapenem-resistant A. baumannii complex using the disk diffusion method and to detect carbapenemase production using the CarbAcineto NP test in isolates from patients at Mae Sot Hospital, Tak Province, in 2023.
The study found that the prevalence of carbapenem-resistant A. baumannii complex was 78.6% (180/229). The highest number of resistant isolates was found in the medical ward, followed by the surgical ward and Intensive Care Unit, accounting for 43.9% (79/180), 27.8% (50/180), and 20.0% (36/180), respectively. The most common specimen types were sputum, pus, and urine, representing 66.1% (119/180), 13.3% (24/180), and 11.7% (21/180), respectively. Most carbapenem-resistant A. baumannii complex isolates remained susceptible to tigecycline 92.2% (166/180). Carbapenemase production was detected in 64.6% (113/175) of the isolates tested. These findings can be used as a guideline for physicians in patient treatment and for the control and prevention ofthe spread of drug-resistant bacteria at Mae Sot Hospital.
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