Prevalence of Metabolic Syndrome in Patients with Major Depressive Disorder at Outpatient Clinic, Department of Psychiatry, Siriraj Hospital

Abstract

ABSTRACT
Objective: To determine the prevalence of metabolic syndrome and its’ associated factors in patients with major depressive disorder at outpatient clinic, department of psychiatry, Siriraj hospital.
Method: A descriptive cross-sectional study was conducted. Sample consisted of 110 patients who were diagnosed as major depressive disorder and visited at outpatient clinic, department of psychiatry, Siriraj hospital, between 23 August and 1 December 2010. They
were assessed by measuring their height, body weight, waist circumference and blood pressure. Blood was drawn for fasting plasma glucose and lipid profile (triglyceride and HDL). Metabolic syndrome was diagnosed by International Diabetes Federation (IDF)
criteria of metabolic syndrome and the prevalence was calculated. Data was analyzed by using percentage, mean, standard deviations, student t-test, chi-square test and Fisher’s exact test.
Results: The prevalence of metabolic syndrome in patients with major depressive disorder at outpatient clinic, was 31.3 %. Occupation, diabetes mellitus, antidiabetic agents, hypertension, antihypertensive agents, dyslipidemia, dyslipidaemic agents and
age were significantly correlated with metabolic syndrome. (p≤0.05).
Conclusion: The metabolic syndrome is quite high prevalence in patients with major depressive disorder. These findings support the importance of assessing and monitoring metabolic syndrome in patients with major depressive disorder.