Neuropsychiatric Symptoms in Dementia with Lewy Bodies and Parkinson's Disease with Dementia

Abstract

ABSTRACT
Dementia with synucleinopathies, such as dementia with Lewy bodies and
Parkinson’s disease with dementia, are important in clinical practice of psychiatry and
neurology including geriatric practice. The diseases causes motor, cognitive, behavioral,
and autonomic dysfunction, neuroleptic sensitivity and neuropsychiatric symptoms such
sleep problems, visual hallucination, delusion, depression and anxiety.
Psychiatrists should have knowledge about these diseases and provide treatment in all aspect of patient’s symptoms. Treatment includes both non-pharmacological treatment and pharmacological treatment. harmacological treatment of motor symptoms such as L-dopa can worsening psychosis. Antidepressant drugs such as SSRI can increase amount of motor disability. Therefore, knowledge about adverse effect of pharmacological treatment of patient’s symptoms could help physician in planning and
adjusting treatment in order to receiving optimal results and not worsening other symptoms.