The Prevalence and Associating Factors with Obesity in Thai Patients With Schizophrenic at Somdet Chaopraya Institute of Psychiatry

Abstract

ABSTRACT
Objective: To determine the prevalence of obesity in schizophrenic patients and to distinguish the factors associated with obesity. To determine the difference between the prevalence of patients receiving conventional antipsychotic drugs and patients receiving atypical antipsychotic drugs.
Materials and Methods: A cross-sectional descriptive study was conducted by pooling
a sample of 2,019 schizophrenic patients at the outpatient clinic, Somdet Chaopraya Institute of Psychiatry from 1st August 2009-January 2010. Percentage and mean. SD were used in analyzing demographic data. Factors associated with obesity were analyzed by using univariate analysis to define OR and 95 % CI and Chi Square and t-test to define p-value. Logistic regression was used to find the most common associated factors with obesity.
Results: The prevalence of obesity was 39.45 % and obesity level II was 11.31 %. In logistic
regression analysis, associated factors with obesity were a family history of obesity (OR=1.63,
95 % CI=1.33-2.00, p=0.000) , a family history of diabetes (OR=1.29, 95 % CI=1.05-1.57, p=0.016),
no smoking exposure (OR=1.17, 95 % CI=1.17-1.83, p=0.001), no amphetamine exposure (OR=2.18, 95 % CI=1.21-3.91, p=0.009) and receiving sodium valproate (OR=1.54, 95 % CI=
1.12-2.13, p=0.008) with statistic significance.
Conclusion: The prevalence of obesity was 39.45 %. Statistical significance of factors associated with obesity was found in those who had a family history of obesity, a family history of diabetic,
no smoking exposure, no amphetamine exposure and receiving sodium valproate.