Air Pollution-Related Kidney Disease in Urban Medicine
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Abstract
Air pollution, particularly particulate matter (PM), is a significant environmental issue that affects various bodily systems and is linked to an increased incidence of illness. It leads to more hospitalizations, reduced quality of life, and higher mortality rates, especially in urban areas where people are continuously exposed to PM from transportation and industrial activities. Studies now suggest that long-term exposure to toxic PM particles can accumulate in the body, affecting kidney function and contributing to the development of chronic kidney disease (CKD). The underlying pathology involves several mechanisms. PM triggers inflammatory responses, damages the lining of blood vessels, and causes arterial constriction. These effects, combined with proteinuria, progressively impair kidney function, eventually leading to CKD. This knowledge can be used to develop preventive measures and treatment strategies for patients at risk of CKD due to air pollution exposure in the future.
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