Combination immunosuppressive therapy in pediatric severe aplastic anemia: trends in response and clinical outcomes

Authors

  • Patcharee Komvilaisak Department of Pediatrics, Faculty of Medicine, Khon Kaen University

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References

Uaprasert N, Chansung K, Pongtanakul B, Lauhasurayotin S, Sirachainan N, Visuthisakchai S, et al. Guideline for diagnosis and management of aplastic anemia in Thailand 2020. J Hematol Transfus Med. 2020;30:405-13.

Peffault de Latour R, Kulasekararaj A, Iacobelli S, Terwel SR, Cook R, Griffin M, et al. Eltrombopag added to immunosuppression in severe aplastic anemia. N Engl J Med. 2022;386:11-23.

Shimamura A, Maschan A, Bennett C, Samarasinghe S, Farrar JE, Li CK, et al. Eltrombopag in combination with immunosuppressive therapy in pediatric severe aplastic anemia: phase 2 ESCALATE trial. Blood Adv. 2025;9:3728-38.

Zhao Y, Yang W, Zhao X, Hu X, Hu J, Liu X, et al. Efficacy of eltrombopag with immunosuppressive therapy for children with acquired aplastic anemia. Front Pediatr. 2023;10:1095143.

Scheinberg P. Activity of eltrombopag in severe aplastic anemia. Blood Adv 2018;2:3054-62

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Published

2026-07-01

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Section

บทบรรณาธิการ (Editorial)