Comparison Between Hemoglobinopathy Disorders Detection by Screening Test and Hemoglobin Typing

Authors

  • Viroj Wiwanitkit Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University
  • Jamsai Suwansaksri Department of Clinical Chemistry, Faculty of Allied Health Science, Chulalongkorn University
  • Nara Paritpokee Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University
  • Atchasai Siritantikorn Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University

Keywords:

Hemoglobin disorder, Pregnancy, Hemoglobin typing, DCIP test

Abstract

Abstract: Hemoglobin disorders is one important health problem in Thailand. In this study, 99 pregnant subjects who attended antenatal clinic, King Chulalongkom Memorial Hospital were included. Screening test for hemoglobinopathy disorders using DCIP- clear test was performed. Hemoglobin electrophoresis was also performed as standard test. From this study, 38:3% of all subiects had hemoglobin disorders. Considering screening for hemoglobin disorders, the sensitivity was 100%, specificity was 97%, positive predictive value was 94% and negative predictive value was 100%. Considering screening for all hemoglobin disorders, the sensitivity was 100%, specificity was 100%, positive predictive value was 100% and negative predictive value was 100%.

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References

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Published

2018-12-30

Issue

Vol. 10 No. 1: January-March 2000

Section

นิพนธ์ต้นฉบับ (Original article)

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.