Prednisolone versus high-dose dexamethasone in newly diagnosed primary immune thrombocytopenia: which is more effective?

Authors

  • Nattiya Teawtrakul Department of Medicine, Faculty of Medicine, Khon Kaen University

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References

Marieke Schoonen W, Kucera G, Coalson J, Li L, Rutstein M, Mowat F, et al. Epidemiology of immune thrombocytopenic purpura in the General Practice Research Database. British journal of haematology. 2009;145:235–44.

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Provan D, Stasi R, Newland AC, Blanchette VS, Bolton-Maggs P, Bussel JB, et al. International consensus report on the investigation and management of primary immune thrombocytopenia. Blood. 2010;115:168–86.

Cines DB, Bussel JB. How I treat idiopathic thrombocytopenic purpura (ITP). Blood. 2005;106:2244–51.

Mithoowani S, Gregory-Miller K, Goy J, Miller MC, Wang G, Noroozi N, et al. High-dose dexamethasone compared withprednisolone for previously untreated primary immune thrombocytopenia: a systematic review and meta-analysis. Lancet Haematol. 2016;3:e489–96.

Jm U, P D, K G, A K, Dr A, Vr B. Initial management of immune thrombocytopaenia in adults based on risk stratification. Postgraduate medical journal [Internet]. 2019 [cited 2024 May 19];95. Available from: https://pubmed.ncbi.nlm.nih.gov/31320499/

Cheng Y, Wong RSM, Soo YOY, Chui CH, Lau FY, Chan NPH, et al. Initial treatment of immune thrombocytopenic purpura with high-dose dexamethasone. N Engl J Med. 2003;349:831–6.

Mazzucconi MG, Fazi P, Bernasconi S, De Rossi G, Leone G, Gugliotta L, et al. Therapy with high-dose dexamethasone (HD-DXM) in previously untreated patients affected by idiopathic thrombocytopenic purpura: a GIMEMA experience. Blood. 2007;109:1401–7.

Sadeghi A, Hosseini SF, Jouzdani SR. Evaluation of treatment plan by three-period pulses of high-dose dexamethasone among patients with primary immune thrombocytopenia on platelet count response and adverse events: a randomized Clinical trial. J Res Med Sci. 2020;25:88.

Mazzucconi MG, Rodeghiero F, Avvisati G, De Stefano V, Gugliotta L, Ruggeri M, et al.prednisolone vs high-dose dexamethasone in newly diagnosed adult primary immune thrombocytopenia: a randomized trial. Blood Advances. 2024;8:1529–40.

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Published

2024-06-23

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บทบรรณาธิการ (Editorial)