Guideline for Diagnosis and Management of Aplastic Anemia in Thailand 2020


  • Noppacharn Uaprasert
  • Kanchana Chansung
  • Bunchoo Pongtanakul
  • Supanun Lauhasurayotin
  • Nongnuch Sirachainan
  • Wichai Prayoonwiwat
  • surapol issaragrisil


Aplastic anemia, diagnosis, treatment, guidelines


Aplastic anemia is a rare bone marrow disorders due to the failure of bone marrow to form peripheral blood cells. Most of patients have pancytopenia and hypocellular bone marrow mostly secondary to immune-mediated destruction of hematopoietic stem cells. Although aplastic anemia is a rare disease, it is associated with significant morbidity and mortality. Currently, the outcomes of plastic anemia have been improved due to a new treatment  such as thrombopoietin receptor agonists as well ass substantial improvement in supportive care, especially antimicrobial agents and transfusion support. The Aplastic Anemia Commitee of Thai Society of Hematology has revised the previous 2011 guidelines using the Guide to Develop Clinical Practice Guidelines which has been endorsed by the Royal College of Physician of Thailand. The draft revised Aplastic Anemia Guidelines were available for public comment before the approval.  


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