การศึกษาประสิทธิภาพและเปรียบเทียบการใช้ Filter 2 ชนิดิ ระหว่าง Sepacell R-500(II) และ Sepacell RZ-200B1 ใน Pre-storage Leukocyte Reduction

Authors

  • ลักษมี กลัญชัย Department of Transfusion Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University
  • ศศิจิต เวชแพศย์ Department of Transfusion Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University
  • วิโรจน์ จงกลวัฒนา Department of Transfusion Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University
  • อุษณีย์ ศิริบุญฤทธิ์ Department of Transfusion Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University
  • กรองทิพย์ วิจิตรจินดา Department of Transfusion Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University
  • วราภรณ์ สุรัตนรังสรรค์ Department of Transfusion Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University

Keywords:

Leukoreduction filter

Abstract

Abstract:

This study was performed to evaluate the effectiveness of pre-storage filtration by the use
of  leukocyte reduction filters for red cells, Sepacell R-500(II) Baxter USA and Sepacell RZ-200B1 Asahi
Medical  Japan. In 2002-2003 Sepacell R-500(II) was used to remove leukocyte from 149 units of adsol
red  cells and red cells. The mean of WBC removal was 99.982%, residual WBC 0.58X106 cells/unit and
RBC  recovery 88.2%. The mean time for filtration was 20.40 minutes. In 2003 Sepacell RZ-200B1 was
used  to remove leukocyte from 65 units of whole blood, adsol red cells and red cells. The mean of WBC
removal  was 99.99%, residual WBC 0.28X106 cells/unit and RBC recovery 91.13%. The mean time for
filtration  was 13.28 minutes. Leukocyte - reduced red cells received from the two filters reached standard
 value and we found that Sepacell RZ-200B1 was significantly better in WBC removal with more
RBC  recovery than Sepacell R-500 (II). In addition Sepacell RZ-200B1 had taken shorter time for filtration
shorter  than Sepacell R-500 (II).

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Published

2019-09-27

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นิพนธ์ต้นฉบับ (Original article)