Blood Transfusion in A Selective IgA Deficiency Patient : A Case Report

บทคัดย่อ

Abstract:

A case report of the male patient with selective IgA deficiency who was diagnosed empyema
thoracis  of left lung and did not respond to antibiotics treatment. The patient was planned for surgical
thoracotomy  and decortication of left lung. Blood was requested for 2 units of packed red cell. Selective
IgA  deficiency was always a problematic in transfusion medicine because the patient may develop
severe  or fatal anaphylactic transfusion reaction following blood or blood components transfusion containing
 IgA. Patient with IgA deficiency disease is rare and blood for  transfusion needs special preparation.
 Blood was usually prepared from either IgA deficiency individuals or washed red cells to reduce
level  of IgA. This patient had blood transfusion which prepared from his IgA deficiency twin and  by
washing  red cells. The patient had massive bleeding intra-operatively and need more blood. In addition
 3 units of washed packed red cells were prepared urgently and fibrin sealant was also used. Postoperatively
 the patient developed shock and wheezing  lung  but  responded very well to medications.
Patient’s  clinical condition was improved in the following day and returned home 9 days  later.