Blood Glucose Level and Hematological Values in Diabetic Rats Received Leaf Extract from Clerodendrum disparifolium Blume.
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Abstract
This study aimed to investigate blood glucose level and hematological values in diabetic rats treated
with the leaf extract from Clerodendrum disparifolium Blume. Rats were induced to be diabetes by giving a
single peritoneal injection of 65 mg/kg streptozotocin. The rats with the fasting blood glucose level above
126 mg/dl were used as diabetic rats. The extract at a dose of 250 mg/kg was given orally and daily to the diabetic rats for 8 weeks. The blood glucose level of the treated rats was determined weekly. The
hematological values; packed cell volume, hemoglobin concentration, red blood cell count, and white
blood cell count were measured at the end of the experiments. The results showed that the extract can
recover the diabetic state in the experimental animals in this study by lowering the blood glucose level and
produce the hematological value in diabetic rats closely to the normal controls.
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