Antioxidant Activity and Total Phenolic Contents of Some Thai Traditional Formulation
Article Sidebar
Main Article Content
Abstract
Introduction: Antioxidants decrease the amount of free radicals and reactive oxygen species in vivo. The traditional herbal medicines have been reported fortheir good antioxidant activities. Thai traditional herbal formulations consist of various herbs with different amounts which could treat many symptomsof gastrointestinal, cardiovascular, respiratory, central nervous systems, musculoskeletal and joint diseases, etc. Many preparations have long been used in Thailand such as Ya-Hom, Ya-Kasaisen, Ya-KeawHomand Ya-Lom. The objectives of this study were to investigate the antioxidant activity and total phenolic contents of seven types of Thai traditional herbal formulations. Methods: Antioxidant activity of seven Thai traditional for mulations was investigated using ABTS radical scavenging assay, and the amount of total phenolic contents was examined using Folin-ciocalteu method. Results: Ya-A formulation showed the highest antioxidant activity (IC50 1.60 mg/mL), while Ya-F formulation showed the lowest antioxidant activity (IC5017.11 mg/mL). The percentage of inhibition of the absorbance of the ABTS+was increased with the increased Thai traditional concentration. Ya-A formulation showed the highest total phenolic contents (891.78 mg GAE/g dry weight). Whereas, the total phenolic contents of Ya-G formulation had the lowest values (158.15 mg GAE/g dry weight). Conclusion: All seven types of Thai traditional herbal formulations had the antioxidant activity and contained phenolic compounds. Ya-A formulation comprising Dracaena loureiri Gagnep.,Ligusticum striatum DC.,Jasminum sambac L., Mimusopselengi L., Mesuaferrea L., Mammeasiamensis T. and Nelumbonucifera Gaertn. Exhibited higher antioxidant activity and total phenolic contents than other test Thai traditional herbal formulations. Therefore, the component in Ya-A was interesting for further investigating antioxidant and other biological activities
Article Details
In the case that some parts are used by others The author must Confirm that obtaining permission to use some of the original authors. And must attach evidence That the permission has been included
References
Channarong S, Jutiviboonsuk A, Korsanan S. Total reducing antioxidant capacity of Thai herbal aromatic powder (Ya-hom) measured by FRAP assay. Thai Pharm Health Sci J.2012, 7(3):111-114.
Halliwell B. Antioxidants in human health and disease. Annu Rev Nutr. 1996, 16: 33-50.
Luanchoy S, Tiangkul S, Wongkrajang Y, Temsiririrkkul R, Peungvicha P, Nakornchai S. Antioxidant activity of a Thai traditional formula for longevity. Mahidol Univ J Pharm Sci. 2014, 41(3): 1-5.
Manok S, Limcharoen P. Investigating antioxidant activity by DPPH, ABTS and FRAP assay and total phenolic compounds of herbal extracts in Ya-Hom Thepphachit. Advanced Science. 2015, 15(1): 106-117.
Nawar WF. Lipids. In: Fennema O, editor. Food chemistry. 3rd ed. New York: Marcel Dekker, Inc.1996, p 225-320.
Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Bio Med. 1999, 26: 1231-1237.
Regoli F. Total oxyradical scavenging capacity (TOSC) in polluted and translocated mussels a predictive biomarker of oxidative stress. Aqua Toxicol. 2000, 50: 351-361.
Rice-Evans CA, Miller NJ, Paganga G. Antioxidant properties of phenolic compounds. Trends Plant Sci. 1997, 2: 152-159. Rubalya VS, Neelamegam P. Antioxidant potential in vegetable oil. ResJ ChemEnviron. 2012,16(2): 87-94.
Shalaby EA, Shanab SMM. Comparision of DPPH and ABTS assays for determining antioxidant potential of water and methanol extracts of Spirulina platensis. Indian J Mar Sci. 2013, 42(5): 556-564.
Su L, Yin J, Charls D. Total phenolic contents chelating capacities, and radical scavenging properties of black peppercorn, nutmeg, rosehip, cinnamon and oregano leaf. Food Chem. 2007,100: 990-997.
Suwangasawong W. Reporting Report of adverse drug reaction/adverse drug events from herbal product / Thai traditional drug during 2006-2015, Medicinal Health Product Bulletin. 2016, 19(3): 88-96.
Tuekaew J, Siriwatanametanon N, Wongkrajang Y, Temsiririrkkul R, Jantan I. Evaluation of the antioxidant activities of Ya-HomIntajak, a Thai herbal formulation, and its component plants. Trop J Pharm Res. 2014, 13(9): 1477-1485.
Yan SW, Asmah R. Comparison of total phenolic contents and antioxidant activities of turmeric leaf, pandan leaf and torch ginger flower. Int Food Research J.2010, 17: 417-423.