The Development of Lannea coromandelica Stem Crude Extract Toner.
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Abstract
From the biological activities of many herbs from Chulaporn Dam, Chaiyapoom, it was found that the crude extract of Lannea coromandelica stem have biological activity against bacteria, fungus and virus. It also has low toxicity. It is chosen to formulate toners for inhibit S. aureus. The 0.5 percent toner of Lannea coromandelica stem crude extract was prepared. Glycerin, sorbitol and propylene glycol were used as humectants, ethanol and water were used as solvent and paraben concentrate was used as preservative. The toners have great physical appearance, good adherence, good spreadability and good primary physical stability but can not inhibit S. aureus. These might be due to the concentration of Lannea coromandelica stem crude extract was not high enough, the contact time of products and S. aureus was not long enough or there might be some interaction between the active substances and the toner’s vehicles resulting in decreasing the antimicrobial activities or retard its activities.
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References
Clinical and Laboratory Standards Institute. 2006. M7-A7. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard, 7th ed. Clinical and Laboratory Standards Institute, Wayne, PA
Lorian V., 1996. Antibiotics in Laboratory Medicine 4th ed. Pensylvania Rose Tree Corporate Center.
Marchetti M, Pisani S, Pietropaolo V, et al., 1996. Antiviral effect of a polysaccharide from Sclertium glucanicum towards herpes simplex virus type 1 infection. Planta Med; 62: 303-307.
National Committee for Clinical Laboratory Standards. 1992. Methods for determining bactericidal activity of antimicrobial agents. NCCLS document M26-T. National Committee for Clinical Laboratory Standards, Villanova, Pa.
Richard MRE, Dorothy KL, Xing JZ., 1993. In vitro evaluation of the antimicrobial activities of selected lozenges. J Pharm Sci.; 82(12): 1218-1220.
Shigeta S, Mori S. Baba M, et al., 1992. Antiviral activities of ribavirin, 5-ethynyl-1-β-D-ribofuranosylimidazole-4-carboxamide, and 6-(R) -6’- C-methylnephanocin A against several ortho - and paramyxoviruses. Antimicrob Agents Chemother; 36(2):435-439.