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From the biological activities of many herbs from Chulaporn Dam, Chaiyapoom, it was found that the crude extract of Lannea coromandelica stem have biological activity against bacteria, fungus and virus. It also has low toxicity. It is chosen to formulate toners for inhibit S. aureus. The 0.5 percent toner of Lannea coromandelica stem crude extract was prepared. Glycerin, sorbitol and propylene glycol were used as humectants, ethanol and water were used as solvent and paraben concentrate was used as preservative. The toners have great physical appearance, good adherence, good spreadability and good primary physical stability but can not inhibit S. aureus. These might be due to the concentration of Lannea coromandelica stem crude extract was not high enough, the contact time of products and S. aureus was not long enough or there might be some interaction between the active substances and the toner’s vehicles resulting in decreasing the antimicrobial activities or retard its activities.
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