Multifunction of Saffron and Its Components in Brain

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Crocus sativus saffron crocin Neuroprotection learning and memory LTP non REM sleeping

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Nguyen Huu Tung
Faculty of Pharmaceutical Science, Nagasaki International University, Sasebo, Nagasaki, Japan
Shinji Soeda
Faculty of Pharmaceutical Science, Fukuoka University, Fukuoka, Japan
Hiroshi Saito
Faculty of Pharmaceutical Science, The University of Tokyo, Tokyo, Japan
Kosuke Aritake
Department of Molecular Behavioral Biology, Osaka Bioscience Institute, Suita, Osaka, Japan
Yukihiro Shoyama
Faculty of Pharmaceutical Science, Nagasaki International University, Sasebo, Nagasaki, Japan

Abstract

Abbreviation: BSO; Buthionine sulfoximine, DMEM; Dulbecco’s modifi ed Eagle’s medium, ELISA; Enzyme-linked immunosorbent assay, FB1; Fumonisin B1, c-GCS; c-Glutamylcysteinyl synthase, GPx; Glutathione peroxidase, GR; Glutathione reductase, GSH; Glutathione, IL-6; Interleukin-6, JNK; c-Jun kinase, LTP; Long-term potentiation, MAb; Monoclonal antibody, NGF; Nerve growth factor, NMDA; N-methyl-D-aspartate, N-Smase; Neutral sphingomyelinase, PS; Phosphatidylserine, SAPK; Stress-activated protein kinase, SD; Step down, SM; Sphingomyelin, SOD; Superoxide dismutase ST; Step through, TNF-a; Tumor necrosis factor

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Vol. 10 (2015): Volume 10 (Supplement), January 2015
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