Antibacterial Consumption and Costs in Inpatients of a Community Hospital
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Abstract
The World Health Organization (WHO) has reported a continuous rise in bacterial resistance, accompanied by a decline in the effectiveness of antibiotics. This trend has led to increased mortality rates and escalating treatment costs. Surveillance and stewardship of antibacterial drug use at the hospital level represent essential strategies for the effective prevention and containment of antimicrobial resistance. Objectives: To analyze the value and consumption of injectable antibacterial drugs in Defined Daily Dose (DDD) form classified by list and group of antibacterial drugs available in Chatturat Hospital during 1 October 2021 – 30 September 2023. Methods: Descriptive research by searching for data on the prescription of injectable antibacterial drugs in inpatients at Chatturat Hospital from the HOSxP database and by using the RDUR9 program (version 63.01.01) of Health Region 9 to analyze the DDD value and calculate the prescription value based on the purchase price of each year. The data were analyzed by using descriptive statistics and simple linear regression statistics. Results: The total value of injectable antibacterial drugs for the fiscal years of 2021-2023 was found to be 2,992,767 baht. Individually, the fiscal years reported values of 907,482 baht, 887,663 baht and 1,197,622 baht, respectively. The value of injectable antibacterial drugs used increased by a mean of 14.54 percent per year. When the consumption of injectable antibacterial drugs by drug group was considered for all 3 fiscal years, it was found that the top 3 injectable antibacterial drugs were third-generation cephalosporins, lincosamide and nitroimidazoles, respectively. The top 3 items with the highest usage value were meropenem, ceftazidime and ceftriaxone at 671,797 baht, 562,080 baht and 440,217 baht or 22.45%, 17.58% and 14.71% of the total value of injectable antibacterial drugs, respectively. As for the amounts of injectable antibacterial drugs used in the DDD unit in the inpatient department in the fiscal years 2021-2023, the top three injectable antibacterial drugs in the DDD unit in the inpatient department were ceftriaxone, clindamycin and ceftazidime at 43.77, 16.34 and 11.32, respectively. Conclusions: During the study period from the fiscal years 2021 - 2023, the prescription value of injectable antibacterial drugs at Chatturat Hospital increased by a mean of 14.54% per year. The volume of injectable antibacterial drugs in the DDD unit tends was in an upward trend at a mean of 24.20% per year.
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