Utilization of Anti-Secretory Drugs for Stress Ulcer Prophylaxis in General Internal Medicine Wards

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Areerut Leelathanalerk
Suratchada Chanasopon
Terdkiad Thiminkul
Narin Tiangboon


Recent studies have shown that stress ulcer prophylaxis (SUP) is overutilized in inpatient medicine wards. Objective: To evaluate the utilization of antisecretory-drugs for SUP in general internal medicine services during hospital stay or at hospital discharge. Materials and Method: This study was a retrospective chart review of adult internal medicine patients admitted in hospital over a 1-year period. The number of patients receiving antisecretory drugs for SUP with the indications suggested by the American Society of Health-System Pharmacists (ASHP) guidelines were assessed. Results: Of the 200 patients who met inclusion criteria, 97 (48.5%) patients were prescribed antisecretory-drugs for SUP appropriately based on the guideline. A total of 103 patients received antisecretory-drugs without any indication. Of these, 52 patients (50.5%) continued antisecretory-drugs upon discharge. Conclusion: SUP was utilized inappropriately in patients admitted in general internal medicine wards. Moreover, antisecretory-drugs were frequently continued upon discharge without the indication. The overutilization of these medications may contribute increased risks of significant side effects and increased healthcare costs.


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Pharmaceutical Practice


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