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The study of pharmaceutical care in patients with acute coronary syndrome was performed in medical wards at Srinagarind Hospital, Khon Kaen. The aim of this study were to determine the risk of death in coronary artery disease patients, to explore drug related problems and to evaluate patients’ knowledge and drug use behavior before and after received pharmacist’s couseling. This study was a prospective descriptive design, which was undertaken during July 1 to September 30, 2005. There were 24 patients with acute coronary syndrome enrolled in this study. The results showed that most patients (41.18%) were at high level in coronary risk of death. Fifty-five drug-therapy problems were identified from 21 patients and solved by a pharmacist. Most common drug-related problems were poor drug adherence (22 events or 40%), not following instructions for modifying risk factors (12 events or 21.82%) and untreated indication (7 events or 12.73%). Pharmacist solved 45 events and prevented 10 events. Pharmaceutical care improved the knowledge of patients about disease, the drug therapy and coronary risk factors with a statistically significant difference, (p<0.001). In conclusion, pharmaceutical care could help the patients in identifing, correcting and preventing the drug therapy problem in patients with acute coronary syndrome and may improve clinical outcome of the patients.
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