Evaluation of Immunomodulating Activity of Selected Thai Medicinal Plants by Lymphocytes Proliferation A ssay

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Chutinun Prasitpunprccha
Bungorn Sripanidkulchai
Viraphong Lulitanond
Jaratbhan Saguansermsri


Forty extracts of indigenous Thai medicinal plants having ethnomedical application in the treatment of chronic diseases and immunological disorders by local practitioners of Ubon Rathathani were investigated for their immunobiological activity. They were studied for mouse spleenic lymphocyte proliferation in the absence and presence of mitogens by colorimetric MTT assay. Among these extracts, three plants displayed strong immunostimulating activities: Dendrophthoe pentandra, Croton cascarilloides, Bauhinia penicilliloba. Three plants showed potential to be immunosupressors: Crateva adansonii, Polygala chinensis, Chionanthus ramiflorus. These results are discussed in relation with traditional medicine.


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