Role of Natural Antioxidants for Topical Applications: Properties, Efficacy, Safety and Novel Delivery Systems

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Sureewan Duangjit
Kornkanok Suwannarat
Kullapas Kittiphinitnunta
Pichnaree Ongwisut
Sureewan Bumrungthai
Tanasait Ngawhirunpat
Ponwanit Charoenputtakun
Warisada Sila-On


Recently, world consumers are more concerned for their health, beauty and appearance. This trend indicates an enormous demand for natural health care products including cosmetic and nutraceutical formulations. The properties, the efficacy, the safety and the stability are primary factors well known that scientists play attention in the design and development of health care, cosmetic and pharmaceutical products. Natural antioxidants are active ingredient that has several health and beauty benefits such as anti-oxidant, anti-ageing, anti-wrinkle and skin lightening properties that make them widely used in health care and cosmetic products. Nanotechnology is one of the most extensively technology utilized in novel delivery systems for pharmaceutical and natural products. The application of nanotechnology for transdermal delivery of natural antioxidants may support the health care products and cosmetics absolute unique, potential and versatile delivery systems. Nanotechnology, such as micelles, liposomes, microemulsions, nanoemulsions, solid lipid nanoparticles, nanostructure lipid carriers, is frequently used to improve the efficacy of skin delivery and targeting. In this review describes the concept of health care and cosmetic products, cause of skin-aging, free-radicals, antioxidants and the recent nanotechnology for transdermal delivery of natural antioxidants used in health care products and cosmetics.


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