The Relationship between Hyperuricemia and Anemia in Postmenopausal Korean Women

Hyun Yoon; Sun Gyu Kim; Mi Young Gi; Ju Ae Cha; So Young Park; Cho Hee Park; Hyun Ho Sung; Eun Sook Han

Authors

Hyun Yoon Department of Clinical Laboratory Science, Wonkwang Health Science University https://orcid.org/0000-0003-2310-4307
Sun Gyu Kim Department of Nursing, Christian College of Nursing https://orcid.org/0000-0002-9150-7290
Mi Young Gi Department of Nursing, Christian College of Nursing
Ju Ae Cha Department of Nursing, Chunnam Technouniversity https://orcid.org/0000-0002-3021-8794
So Young Park Department of Dental Hygiene, Wonkwang Health Science University https://orcid.org/0000-0003-0746-218X
Cho Hee Park Department of global Medical Beauty, Konyang University
Hyun Ho Sung Department of Clinical Laboratory Science, Dongnam Health University
Eun Sook Han Department of Public Relations, Seoul National University Bundang Hospital

Keywords:

anemia, uric acid, hyperuricemia, women, menopause

Abstract

Objective The present study was conducted to assess the association of hyperuricemia and anemia in premenopausal and postmenopausal Korean women.

Methods Data from 9,239 adults (aged ≥ 20 years) in the Korean National Health and Nutrition Examination Survey VII (2016–2018) were analyzed.

Results After adjustment for related variables (including age), the odds ratio (OR) of hyperuricemia (uric acid [UA] < 6.0 mg/dL), using the normal group (hemoglobin [Hb] ≥ 12.0 g/dL) as a reference, was statistically significantly positively associated with the anemia group (Hb < 12.0 g/dL) in postmenopausal women (OR, 1.615; 95% CI, 1.187–2.198). In premenopausal women, after adjustment for the related variables (except age), the OR of hyperuricemia, with a normal group as a reference, was significantly inversely associated with the anemia group (OR, 0.583; 95% CI, 0.348–0.975). However, with further adjustment for age, hyperuricemia was no longer associated with anemia (OR, 0.679; 95% CI, 0.402–1.148).

Conclusions Hyperuricemia is positively associated with anemia in postmenopausal women but not in premenopausal women.

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