Radiological and Functional Outcomes of Conservatively Managed Osteoporotic Vertebral Fractures at the Thoracolumbar Junction: A cross sectional study

Authors

  • Shankar Acharya Department of Ortho-Spine Surgery, Sir Ganga Ram Hospital, India https://orcid.org/0000-0002-6966-5698
  • Jagadish Thapa Department of Orthopaedic and Traumatology, Dhulikhel Hospital, Kathmandu University School of Medical Sciences, Nepal https://orcid.org/0000-0002-5124-8159
  • Rupinder Singh Chahal Department of Ortho-Spine Surgery, Sir Ganga Ram Hospital, India
  • Kashmiri Lal Kalra Department of Ortho-Spine Surgery, Sir Ganga Ram Hospital, India
  • Deepak Kaucha Department of Orthopaedic and Traumatology, B & B Hospital Pvt. Limited, Nepal

Keywords:

conservative management, osteoporotic, thoracolumbar, vertebral fracture

Abstract

OBJECTIVE This study examined how osteoporotic vertebral fracture (OVF) patients treated conservatively at a multi-specialty hospital were progressing clinically and radiologically.

METHODS This cross sectional, observational study was conducted at Sir Ganga Ram Hospital, New Delhi, India during the period of July 2021 to October 2021. Cases with at least a 6-month follow-up were evaluated. VAS pain score, Oswestry Disability Index (ODI), and local kyphotic angle (COBB’s angle) at the time of fracture and at the latest follow-up were recorded and analyzed.

RESULTS There were 30 patients (female: male = 2.75:1) with a mean age of 67.37 years (45-85). The average VAS score at the time of fracture
was 8 (6 to 10) and at the time of final follow-up was 2 (1 to 6) (p = 0.001). The average ODI score at the time of fracture was 44 (35 to 62) and at the time of final follow up was 5 (4 to 40) (p = 0.001). The average Cobb’s angle at the time of fracture was 14.31o and at the final follow up was 15.66o (p = 0.011).

CONCLUSIONS Conservative management of OVF can lead to an increase in the local kyphotic angle. The fact that the patients experienced significant decreases in VAS pain scores and ODI scores by the final follow-up leads to the conclusion that patients can have a good quality of life even with conservative management of osteoporotic vertebral fractures.

 

References

Zhao S, Xu CY, Zhu AR, Ye L, Lv LL, Chen L, Huang Q, Niu F. Comparison of the efficacy and safety of 3 treatments for patients with osteoporotic vertebral compression fractures: a network meta-analysis. Medicine. 2017;96(26):e7328 PubMed PMID:28658144.

Francis RM, Baillie SP, Chuck AJ, Crook PR, Dunn N, Fordham JN, Kelly C, Rodgers A. Acute and long-term management of patients with vertebral fractures. QJM. 2004;97:63-74.

Venmans A, Klazen CA, Lohle PN, Mali WP, Van Rooij WJ. Natural history of pain in patients with conservatively treated osteoporotic vertebral

compression fractures: results from VERTOS II. AJNR Am J Neuroradiol. 2012;33:519-21.

Thomas RJF-de, Jesus O de. Thoracolumbar spine fracture. Key Topics in Sports Medicine [Internet]. 2021 [cited 2022 Jul 30];299-303. Available from: https://www.ncbi.nlm.nih.gov/books/NBK562204/

Heary RF, Kumar S. Decision-making in burst fractures of the thoracolumbar and lumbar spine. Indian J Orthop. 2007;41:268-76.

Schnake KJ, Blattert TR, Hahn P, Franck A, Hartmann F, Ullrich B, Verheyden A, Mörk S, Zimmermann V, Gonschorek O, Müller M. Classification of osteoporotic thoracolumbar spine fractures: recommendations of the spine section of the German Society for Orthopaedics and Trauma (DGOU). Global Spine J. 2018;8(supplement_2):S46-S9.

Sugita M, Watanabe N, Mikami Y, Hase H, Kubo T. Classification of vertebral compression fractures in the osteoporotic spine. J Spinal Disord Tech. 2005;18:376-81.

Blattert TR, Schnake KJ, Gonschorek O, Gercek E, Hartmann F, Katscher S, et al. Nonsurgical and surgical management of osteoporotic vertebral body fractures: Recommendations of the spine section of the German Society for Orthopaedics and Trauma (DGOU). Global Spine J. 2018;8(supplement_2):S50-S5.

Haefeli M, Elfering A. Pain assessment. Euro Spine J. 2006;15(Supplement_1):S17-S24

Fairbank JC, Pynsent PB. The Oswestry disability index. Spine. 2000;25(22):2940-53.

Shah S, Goregaonkar AB. Conservative management of osteoporotic vertebral fractures: a prospective study of thirty patients. Cureus. 2016;8(3):e542 PubMed PMID: 27158572.

Warming L, Hassager C, Christiansen C. Changes in bone mineral density with age in men and women: a longitudinal study. Osteoporosis Int. 2002;13:105-12

Pinheiro MM, Reis Neto ET, Machado FS, Omura F, Yang JH, Szejnfeld J, Szejnfeld VL. Risk factors for osteoporotic fractures and low bone density in pre and postmenopausal women. Rev Saude Publica. 2010;44:479-85.

Park YS, Kim HS. Prevention and treatment of multiple osteoporotic compression fracture. Asian Spine J. 2014;8:382-90.

Nevitt MC, Chen P, Kiel DP, Reginster JY, Dore RK, Zanchetta JR, Glass EV, Krege JH. Reduction in the risk of developing back pain persists at least 30 months after discontinuation of teriparatide treatment: a meta-analysis. Osteoporosis Int. 2006;17:1630-7.

Nevitt MC, Chen P, Dore RK, Reginster JY, Kiel DP, Zanchetta JR, Glass EV, Krege JH. Reduced risk of back pain following teriparatide treatment: a meta-analysis. Osteoporosis Int. 2006;17:273-80.

Rajasekaran S, Kanna RM, Schnake KJ, Vaccaro AR, Schroeder GD, Sadiqi S, Oner C. Osteoporotic thoracolumbar fractures—how are they different?—Classification and treatment algorithm. J Orthop Trauma. 2017;31(Supplement_4):S49-S56.

Knopp JA, Diner BM, Blitz M, Lyritis GP, Rowe BH. Calcitonin for treating acute pain of osteoporotic vertebral compression fractures: a systematic review of randomized, controlled trials. Osteoporosis Int. 2005;16:1281-90.

Armingeat T, Brondino R, Pham T, Legré V, Lafforgue P. Intravenous pamidronate for pain relief in recent osteoporotic vertebral compression fracture: a randomized double-blind controlled study. Osteoporosis Int. 2006;17:1659-65.

Barker KL, Javaid MK, Newman M, Minns Lowe C, Stallard N, Campbell H, Gandhi V, Lamb S. Physiotherapy Rehabilitation for Osteoporotic Vertebral Fracture (PROVE): study protocol for a randomised controlled trial. Trials. 2014;15:1-11.

Downloads

Published

2023-11-06

How to Cite

1.
Acharya S, Thapa J, Chahal RS, Kalra KL, Kaucha D. Radiological and Functional Outcomes of Conservatively Managed Osteoporotic Vertebral Fractures at the Thoracolumbar Junction: A cross sectional study. BSCM [Internet]. 2023 Nov. 6 [cited 2024 Nov. 21];62(4):142-8. Available from: https://he01.tci-thaijo.org/index.php/CMMJ-MedCMJ/article/view/266985

Issue

Section

Original Article