Successful Treatment of Generalized Pustular Psoriasis Triggered during Pregnancy with Secukinumab: A Case Report

Pattaraporn  Koompawichit; Salin  Kiratikanon; Napatra  Tovanabutra; Siri  Chiewchanvit; Mati  Chuamanochan

Authors

Pattaraporn Koompawichit Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Thailand
Salin Kiratikanon Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Thailand https://orcid.org/0000-0002-1597-7290
Napatra Tovanabutra Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Thailand https://orcid.org/0000-0002-9463-5976
Siri Chiewchanvit Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Thailand https://orcid.org/0000-0001-9634-9650
Mati Chuamanochan Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Thailand https://orcid.org/0000-0002-6654-3409

Keywords:

generalized pustular psoriasis, pregnancy, interleukin-17, secukinumab

Abstract

Secukinumab is one of the biologic drugs targeting interleukin-17 (IL17) which is highly effective in the treatment of generalized pustular psoriasis (GPP). However, there is only limited data regarding treatment with GPP during pregnancy because of the rarity of the disease as well as ethical issues. This study describes the successful treatment with secukinumab of a 10 weeks pregnant women with recurrent GPP.

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