Clinical efficacy of Generic Meropenem (Penem®): Experience of Her Royal Highness Princess Maha Chakri Sirindhorn Medical Center, Faculty of Medicine, Srinakaharinwirot University (ผลการตอบสนองในทางคลินิกต่อยา Generic Meropenem(Penem): ประสบการณ์ของศูนย์)

Authors

  • Wanchai Buppanharun
  • Woraphot Tantisiriw

Abstract

Objective: To review the clinical efficacy of generic meropenem (Penem®) use in 17 patients. Method: A retrospective review of patients receiving Penem® for the treatment of Her Royal Highness Princess Sirindhorn Medical center Faculty of Medicine, Srinakaharinwirot University, Nakornnayok was carried out from December 2007 to May 2008. Results: From nineteen patients (11 males and 8 females) had received Penem® during the study period but 2 patients were excluded due to inadequate duration of treatment and non-susceptible causative pathogen. The infections included urinary tract infection (6 patients), respiratory tract infection (6 patients), intra-abdominal infections (2 patients) and bone-plate infection (1patient). Nine patients had infection caused by single organism, 6 patients had that caused by multiple organisms, and 2 patients had negative culture results. Seven patients had evidence of bacteremia, and 6 patients had evidence of clinical sepsis. Sixteen patients from 17 patients, who were infected with susceptible bacteria to Penem®, were improved with treatment. Conclusion: In our institute, Penem® can be prescribed to treat infections caused by susceptible strains.

Author Biographies

Wanchai Buppanharun

Department of Preventive Medicine, Faculty of Medicine, Srinakharinwirot University

Woraphot Tantisiriw

Department of Preventive Medicine, Faculty of Medicine, Srinakharinwirot University

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Published

2010-08-18

How to Cite

1.
Buppanharun W, Tantisiriw W. Clinical efficacy of Generic Meropenem (Penem®): Experience of Her Royal Highness Princess Maha Chakri Sirindhorn Medical Center, Faculty of Medicine, Srinakaharinwirot University (ผลการตอบสนองในทางคลินิกต่อยา Generic Meropenem(Penem): ประสบการณ์ของศูนย์). J Med Health Sci [Internet]. 2010 Aug. 18 [cited 2024 Mar. 29];16(2). Available from: https://he01.tci-thaijo.org/index.php/jmhs/article/view/61266