ภาวะเหงือกโต (Gingival overgrowth)

Abstract

Gingival overgrowth  is a clinical diagnosis condition. This condition can be caused by either the abnormally increasing number of cells or the size of cells without the increased number. It can be categorized according to the causes, mainly by the medication such as anticonvulsants, immunosuppressive drugs and calcium-channel blockers. This study focuses on the gingival overgrowth, caused by medication, found mostly in childhood. The initial clinical characteristic is the hypertrophy of buccal-side gingival of the incisors after 1-3 months after first administration of the medication. The pathogenesis is yet to be wholly understandable, however, genetic factor and inflammation due to the production and release of chemokines and cytokines are believed to be the culprits. Treatments involve cessation of the causing drug along with the maintenance of oral hygiene as well as antibiotics and anti-inflammatory drugs therapy, surgical intervention is an option in certain cases.