Shift work and metabolic risk factors

Authors

  • Napas Taechasan Department of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University
  • Wiroj Jiamjarasrangsi Department of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University

Keywords:

shift work, metabolic syndrome, hypertension, abdominal obesity, dyslipidemia, diabetes type 2

Abstract

Abstract

Shift work is a form of work with unusual working hours, such as early in the morning or late at night. Previous studies have shown that shift work has several health effects including gastrointestinal diseases, respiratory diseases, breast cancer and chronic non-communicable diseases like metabolic syndrome. Metabolic syndrome is a group of risk factors which include hypertension, prediabetes and diabetes type 2, dyslipidemia, and central obesity contributing to significant causes of cardiovascular disease, such as ischemic heart disease and strokes. The association between shift work and metabolic risk factors have been studied and suggested that shift work increased the incidence of these factors. However, the number of studies and reviews showed the relationship between shift work and all these metabolic risk factors were limited. This review aims to collect the important studies displaying the relationship between shift work, these metabolic risk factors, and the mechanisms contributing to these abnormalities. In addition, the administrative management of shift work schedules and the preparation of shift workers prior to, during and after their shifts were stated. It can be concluded that shift work, particularly night shift work, increases all of the metabolic risk factors through the result of circadian misalignment. The proper design of shift work schedule and the adequate preparation of shift workers can help workers to adapt themselves and decrease effect of shift work on metabolic risk factors.   

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References

International Labour Organization [Internet]. Geneva: Yearly statistics; 2015 [cited 2022 February 16]. [Available from: http://laborsta.ilo.org].

Ministry of Labour. Labour statistics yearbook 2020. 1st ed. Bangkok: The office of permanent secretary;2021:028-29.

Kecklund G, Axelsson J. Health consequences of shift work and insufficient sleep. BMJ 2016;355: i5210.

Wang F, Zhang L, Zhang Y, et al. Meta-analysis on night shift work and risk of metabolic syndrome. Obes Rev 2014;15(9):709-20.

Proper KI, van de Langenberg D, Rodenburg W, et al. The relationship between shift work and metabolic risk factors: a systematic review of longitudinal studies. Am J Prev Med 2016;50(5):e147-e157.

Khosravipour M, Khanlari P, Khazaie S, et al. A systematic review and meta-analysis of the association between shift work and metabolic syndrome: The roles of sleep, gender, and type of shift work. Sleep Med Rev 2021;57:101427.

Shah A, Turkistani A, Luenam K, et al. Is shift work sleep disorder a risk factor for metabolic syndrome and Its components? a systematic review of cross-sectional studies. Metab Syndr Relat Disord 2022;20(1):1-10.

Rosa RR, Colligan MJ. Plain language about shiftwork. Ohio:DHHS (NIOSH);1997:1-36.

Cheng P, Drake C. Shift Work Disorder. Neurol Clin 2019;37(3):563-577.

Solymanzadeh F, Rokhafroz D, Asadizaker M, et al. The relationship between rotating shift work and blood pressure among nurses working in hospitals of Abadan, Iran. Chronobiol Int 2021;1-6.

Khosravipour M, Mohammadi MS, Athar HV, et al. The association between rotating night shift work and hypertension: A cross-sectional study among male workers. Eur J Prev Cardiol 2020;2047487320906921

Hanprathet N, Lertmaharit S, Lohsoonthorn V, et al. Increased risk of type 2 diabetes and abnormal FPG due to shift work differs according to gender: a retrospective cohort study among Thai workers in bangkok, Thailand. Diabetes Metab Syndr Obes 2019;12:2341-2354.

Dutheil F, Baker JS, Mermillod M, et al. Shift work, and particularly permanent night shifts, promote dyslipidaemia: a systematic review and meta-analysis. Atherosclerosis 2020;313:156-69.

Joo JH, Lee DW, Choi DW, et al. Association between night work and dyslipidemia in South Korean men and women: a cross-sectional study. Lipids Health Dis 2019;18(1):75.

Liu Q, Shi J, Duan P, et al. Is shift work associated with a higher risk of overweight or obesity? a systematic review of observational studies with meta-analysis. Int J Epidemiol 2018;47(6):1956-71.

Sun M, Feng W, Wang F, et al. Meta-analysis on shift work and risks of specific obesity types. Obes Rev 2018;19(1):28-40.

Lee GJ, Kim K, Kim SY, et al. Effects of shift work on abdominal obesity among 20-39-year-old female nurses: a 5-year retrospective longitudinal study. Ann Occup Environ Med 2016;28:69.

D'Ettorre G, Pellicani V, Greco M, et al. Metabolic syndrome in shift healthcare workers. Med Lav 2019;110(4):285-292.

Kulkarni K, Schow M, Shubrook JH. Shift workers at risk for metabolic syndrome. J Am Osteopath Assoc 2020;120(2):107-117.

Torquati L, Mielke GI, Brown WJ, et al. Shift work and the risk of cardiovascular disease. a systematic review and meta-analysis including dose-response relationship. Scand J Work Environ Health 2018;44(3):229-238.

Ho FK, Celis-Morales C, Gray SR, et al. Association and pathways between shift work and cardiovascular disease: a prospective cohort study of 238 661 participants from UK Biobank. Int J Epidemiol 2022;51(2):579-590.

Xue J, Zhao Y, Wang Z, et al. Rotating night shift work is associated with an increased risk of gastroesophageal reflux disease (GERD) symptoms among workers in China: a cross-sectional study. Int J Clin Pract 2021;75(4):e13848.

Maidstone RJ, Turner J, Vetter C, et al. Night shift work is associated with an increased risk of asthma. Thorax 2021;76(1):53-60.

Cai C, Vandermeer B, Khurana R, et al. The impact of occupational shift work and working hours during pregnancy on health outcomes: a systematic review and meta-analysis. Am J Obstet Gynecol 2019;221(6):563-576.

Rivera AS, Akanbi M, O'Dwyer LC, et al. Shift work and long work hours and their association with chronic health conditions: a systematic review of systematic reviews with meta-analyses. PLoS One 2020;15(4):e0231037.

Torquati L, Mielke GI, Brown WJ, et al. Shift work and poor mental health: a meta-analysis of longitudinal studies. Am J Public Health 2019;109(11):e13-e20.

Lee WT, Lim SS, Kim J, et al. Work schedule irregularity and the risk of work-related injury among Korean manual workers. Int J Environ Res Public Health 2020;17(20):7617.

Alberti G, Zimmet P, Shaw J, et al. The IDF consensus worldwide definition of the metabolic syndrome. Brussels: IDF Communications; 2006:4-12.

Kanchanapiboonwong A, Kumwangsa-ngar P, Kaewta S. Disease situation report of NCDs diabetes type 2, hypertension and related risk factors 2019. Bangkok: Aksorn graphic and design;2020:3-24.

Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults. Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III). JAMA 2001;285(19):2486-2497.

Fagiani F, Marino DD, Romagnoli A, et al. Molecular regulations of circadian rhythm and implications for physiology and diseases. Signal Transduct Target Ther 2022;7(1):41.

Stenvers DJ, Scheer F, Schrauwen P, et al. Circadian clocks and insulin resistance. Nat Rev Endocrinol 2019;15(2):75-89.

Li Y, Ma J, Yao K, et al. Circadian rhythms and obesity: timekeeping governs lipid metabolism. J Pineal Res 2020;69(3):e12682.

Soliman RH, Pollock DM. Circadian control of sodium and blood pressure regulation. Am J Hypertens 2021;hpab100.

Suriagandhi V, Nachiappan V. Protective effects of melatonin against obesity-induced by leptin resistance. Behav Brain Res 2022;417:113598.

American Diabetes Association. 2. Classification and diagnosis of diabetes: standards of medical care in diabetes-2019. Diabetes Care 2019;42(suppl1):S13-S28.

Morikawa Y, Nakagawa H, Miura K, et al. Shift work and the risk of diabetes mellitus among Japanese male factory workers. Scand J Work Environ Health 2005;31(3):179-183.

Osaki Y, Kuwahara K, Hu H, et al. Shift work and the onset of type 2 diabetes: results from a large-scale cohort among Japanese workers. Acta Diabetol 2021;58(12):1659-1664.

Sharma A, Laurenti MC, Man CD, et al. Glucose metabolism during rotational shift-work in healthcare workers. Diabetologia 2017;60(8):1483-1490.

Morris CJ, Purvis TE, Mistretta J, et al. Effects of the internal circadian system and circadian misalignment on glucose tolerance in chronic shift workers. J Clin Endocrinol Metab 2016;101(3): 1066-1074.

Li J, Bidlingmaier M, Petru R, et al. Impact of shift work on the diurnal cortisol rhythm: a one-year longitudinal study in junior physicians. J Occup Med Toxicol 2018;13:23.

Manohar S, Thongprayoon C, Cheungpasitporn W, et al. Associations of rotational shift work and night shift status with hypertension: a systematic review and meta-analysis. J Hypertens 2017;35(10):1929-1937.

Ferguson JM, Costello S, Neophytou AM, et al. Night and rotational work exposure within the last 12 months and risk of incident hypertension. Scand J Work Environ Health 2019;45(3):256-266.

Kubo T, Fujino Y, Nakamura T, et al. An industry-based cohort study of the association between weight gain and hypertension risk among rotating shift workers. J Occup Environ Med 2013;55(9): 1041-1045.

Morikawa Y, Nakagawa H, Miura K, et al. Relationship between shift work and onset of hypertension in a cohort of manual workers. Scand J Work Environ Health 1999;25(2):100-104.

Del Giorno R, Troiani C, Gabutti S, et al. Impaired daytime urinary sodium excretion impacts nighttime blood pressure and nocturnal dipping at older ages in the general population. Nutrients 2020;12(7):2013.

Albreiki MS, Middleton B, Hampton SM. The effect of melatonin on glucose tolerance, insulin sensitivity and lipid profiles after a late evening meal in healthy young males. J Pineal Res 2021;71(4):e12770.

Qian J, Morris CJ, Caputo R, et al. Ghrelin is impacted by the endogenous circadian system and by circadian misalignment in humans. Int J Obes (Lond) 2019;43(8):1644-1649.

McHill AW, Phillips AJ, Czeisler CA, et al. Later circadian timing of food intake is associated with increased body fat. Am J Clin Nutr 2017;106(5):1213-1219.

The National Institute for Occupational Safety and Health (NIOSH) [Internet]. Washington, DC: NIOSH training for nurses on shift work and long work hours; 2015 [cited 2022 June 20]. [available from: http://www.cdc.gov/niosh/work-hour-training-for-nurses/default.html].

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Published

2022-08-31

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Section

Review Article (บทความวิชาการ)