Case report on rhinofacial Conidiobolomycosis caused by Conidiobolus sp.
Keywords:
conidiobolomycosis, entomophthoromycosis, zygomycosis, Conidiobolus coronatus, rhinofacial edemaAbstract
Abstract
Rhinofacial conidiobolomycosis is an uncommon chronic subcutaneous fungal infection in Thailand. This disease mainly affects the mucosa of the nares, nasal passages, sinus, nasopharynx, lip and mouth, causing disfigurement of the midline of the face and nasal obstruction. This article reported a 77-year-old male patient who presented with a nasal obstruction and progressive facial swelling. On histopathological examination of the tissue biopsy and fungal culture, it was determined that a patient was infected with Conidiobolus sp. The patient was successfully treated with a combination therapy of Itraconazole and Terbinafine for six months.
References
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2. Bras G, Gordon CC, Emmons CW, et al. A case of phycomycosis observed in Jamaica; infection with Entomophthora coronata. Am J Trop Med Hyg 1965;14: 141-5.
3. Gugnani HC. Entomophthoromycosis due to Conidiobolus. Eur J Epidemiol1992;8:391-6.
4. Ribes JA, Vanover-Sams CL, Baker DJ. Zygomycetes in Human Disease. Clin Microbiol Rev 2000;13:236-301.
5. Akpanonu BE, Ansel G, Karurich JD, et al. Zygomycosis mimicking paranasal malignancy. Am J Trop Med Hyg 1991; 45:390-8.
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7. Agrawal S, Meshram P, Qazi MS. Rhinoentomophthoromycosis: A rare case report. Indian J Med Microbiol 2013;31:401-3.
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Med Mycol 2010;48:870-9.
9. Prabhu RM, Patel R. Mucormycosis and entomophthoramycosis: A review of the clinical manifestations, diagnosis and treatment, Clin Microbiol Infect 2004;10:31-47.
10. El-Shabrawi MH, Arnaout H, Madkour L, et al. Entomophthoromycosis: A challenging emerging disease. Mycoses 2014;57 (Suppl 3):132-7.
11. Mortez ML, Grist WJ, Sewell CW. Zygomycosis presenting as nasal polyp in a healthy child. Arch Otolaryngol Head Neck Surg 1987;113:550-2.
12. Kaufman L, Mendoza L, Standard PG. Immunodiffusion test for serodiagnosing subcutaneous zygomycosis, J Clin Microbiol 1990;28:1887-90.
13. Sugar AM. Agents of mucormycosis and related species. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett’s principles and practice of infectious diseases. Vol 2. 6th ed. Philadelphia: Churchill Livingstone; 2005. p.2980-1.
14. Chayakulkeeree M, Ghannoum MA, Perfeft JR. Zygomycosis: the re-emerging fungal infection. Eur J Clin Microbiol Infect Dis 2006;25:215-29.
15. Valle AC, Wanke B, Lazéra MS, et al. Entomophthoromycosis by Conidiobolus coronatus. Report of a case successfully treated with the combination of itraconazole and fluconazole, Rev Inst Med Trop Sao Paulo 2001;43:233-6.
16. Leopairut J, Larbcharoensub N, Cheewaruangroj W, et al. Rhinofacial entomophthoramycosis; A case series and review of the literature. Southeast Asian J Trop Med Public Health 2010;41:928-35.
17. Cauteren HV, Heykants J, Coster RD, et al. Itraconazole: Pharmacologic studies in animals and humans. Rev Infect Dis 1987;9:S43-S46.
18. Borelli A. Clinical trial of itraconazole in the treatment of deep mycoses and leishmaniosis. Rev Infect Dis 1987;9: S57-S63.
19. Kabra SK, Jain Y, Sudhin T, et al. Successful treatment of entomophthoromycosis with itraconazole. Indian Pediatr 1998; 35:163-6.
20. Cherian LM, Varghese L, Panchatcharam BS, et al. Nasal conidiobolomycosis: A successful treatment option for localized disease. J Postgrad Med 2015;61:143-4.
2. Bras G, Gordon CC, Emmons CW, et al. A case of phycomycosis observed in Jamaica; infection with Entomophthora coronata. Am J Trop Med Hyg 1965;14: 141-5.
3. Gugnani HC. Entomophthoromycosis due to Conidiobolus. Eur J Epidemiol1992;8:391-6.
4. Ribes JA, Vanover-Sams CL, Baker DJ. Zygomycetes in Human Disease. Clin Microbiol Rev 2000;13:236-301.
5. Akpanonu BE, Ansel G, Karurich JD, et al. Zygomycosis mimicking paranasal malignancy. Am J Trop Med Hyg 1991; 45:390-8.
6. Manning RJ, Waters SD, Callaghan AA. Saprotrophy of Conidiobolus and Basidiobolusin leaf litter. Mycol Res 2007;111:1437-49.
7. Agrawal S, Meshram P, Qazi MS. Rhinoentomophthoromycosis: A rare case report. Indian J Med Microbiol 2013;31:401-3.
8. Chowdhary A, Randhawa HS, Khan ZU, et al. Rhinoentomophthoromycosis due to Conidiobolus coronatus. A case report and an overview of the disease in India.
Med Mycol 2010;48:870-9.
9. Prabhu RM, Patel R. Mucormycosis and entomophthoramycosis: A review of the clinical manifestations, diagnosis and treatment, Clin Microbiol Infect 2004;10:31-47.
10. El-Shabrawi MH, Arnaout H, Madkour L, et al. Entomophthoromycosis: A challenging emerging disease. Mycoses 2014;57 (Suppl 3):132-7.
11. Mortez ML, Grist WJ, Sewell CW. Zygomycosis presenting as nasal polyp in a healthy child. Arch Otolaryngol Head Neck Surg 1987;113:550-2.
12. Kaufman L, Mendoza L, Standard PG. Immunodiffusion test for serodiagnosing subcutaneous zygomycosis, J Clin Microbiol 1990;28:1887-90.
13. Sugar AM. Agents of mucormycosis and related species. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett’s principles and practice of infectious diseases. Vol 2. 6th ed. Philadelphia: Churchill Livingstone; 2005. p.2980-1.
14. Chayakulkeeree M, Ghannoum MA, Perfeft JR. Zygomycosis: the re-emerging fungal infection. Eur J Clin Microbiol Infect Dis 2006;25:215-29.
15. Valle AC, Wanke B, Lazéra MS, et al. Entomophthoromycosis by Conidiobolus coronatus. Report of a case successfully treated with the combination of itraconazole and fluconazole, Rev Inst Med Trop Sao Paulo 2001;43:233-6.
16. Leopairut J, Larbcharoensub N, Cheewaruangroj W, et al. Rhinofacial entomophthoramycosis; A case series and review of the literature. Southeast Asian J Trop Med Public Health 2010;41:928-35.
17. Cauteren HV, Heykants J, Coster RD, et al. Itraconazole: Pharmacologic studies in animals and humans. Rev Infect Dis 1987;9:S43-S46.
18. Borelli A. Clinical trial of itraconazole in the treatment of deep mycoses and leishmaniosis. Rev Infect Dis 1987;9: S57-S63.
19. Kabra SK, Jain Y, Sudhin T, et al. Successful treatment of entomophthoromycosis with itraconazole. Indian Pediatr 1998; 35:163-6.
20. Cherian LM, Varghese L, Panchatcharam BS, et al. Nasal conidiobolomycosis: A successful treatment option for localized disease. J Postgrad Med 2015;61:143-4.
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Published
2021-12-30
How to Cite
1.
Trinusonth N. Case report on rhinofacial Conidiobolomycosis caused by Conidiobolus sp. J Med Health Sci [Internet]. 2021 Dec. 30 [cited 2024 Apr. 26];28(3):139-46. Available from: https://he01.tci-thaijo.org/index.php/jmhs/article/view/254034
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Case Report/Series (รายงานผู้ป่วย)
