Human metabolite profiling changes with organic food consumption for 7 and 30 days: A pilot study

Authors

  • Sasiwimon Lalitmanat Center for Research and Innovation, Faculty of Medical Technology, Mahidol University
  • Supitcha Pannengpetch Center for Research and Innovation, Faculty of Medical Technology, Mahidol University
  • Thummaruk Suksrichavalit 1Center for Research and Innovation, Faculty of Medical Technology, Mahidol University
  • Tararat Khaokhiew Department of Clinical Chemistry, Faculty of Medical Technology, Mahidol University
  • Chartchalerm Isarankura-Na-Ayudhya
  • Arrut Navaraj Suan Sampran, Nakhonpathom
  • Wilasinee Suwanjang Suan Sampran, Nakhonpathom

Keywords:

organic food, healthy food, body mass index, metabolite compounds

Abstract

Abstract
Organic food consumption is a growing interest worldwide. The aim of this study is to assess overall metabolite changes that occur during organic food consumption. The Thai adult participants were classified into two groups, with a normal or at-risk health status, and then provided with a diet containing organic foods for 7 and 30 days. Health checkups,including blood and urine sampling, were performed at 0, 7 and 30 days. The effects on body weight, body mass index, the basal metabolic rate and zinc concentrations showed significantdifferences after 30 days. Urine metabolite profiling showed some changes related to human metabolic pathways. Organic food consumption was associated with higher levels of nicotinamidebeta-riboside, biliverdin, octadecanoic acid, 2-methyl-1-hydroxybutyl-ThPP, s-adenosyll-homocysteine, 2,3-diketo-5-methylthiopentyl-1-phosphate, fumarate and pyridoxal phosphate and lower levels of allopregnanolone, dolichyl beta-d-glucosyl phosphate, corticosterone, dehydroepiandrosterone sulfate,         n-carbamoyl-l-aspartate and leukotriene C4. The observed metabolite changes might indicate the health-related impact of organic food consumption.

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Published

2021-12-30

How to Cite

1.
Lalitmanat S, Pannengpetch S, Suksrichavalit T, Khaokhiew T, Isarankura-Na-Ayudhya C, Navaraj A, Suwanjang W. Human metabolite profiling changes with organic food consumption for 7 and 30 days: A pilot study. J Med Health Sci [Internet]. 2021 Dec. 30 [cited 2024 Mar. 29];28(3):75-89. Available from: https://he01.tci-thaijo.org/index.php/jmhs/article/view/254018