The effects of heat on sperm quality and male infertility: A systematic review
Keywords:
heat, male infertility, sperm, temperatureAbstract
Continuous heat exposure in daily life causes adverse health effects, especially in terms of the structure and the function of the reproductive organs. The objective of this study is to determine the effects of heat from daily life and working on sperm quality and male infertility by a systematic review. The keywords used in this review included fertility, hyperthermia, sperm, sterility and temperature and conducted by searching in the following databases: BMC central, PubMed, and Science Direct from 2010-2020. Among the 33 research articles, five articles met the inclusion criteria. The results showed that internal and environmental heat induced scrotal hyperthermia and reduced the quality of sperm i.e., volume, number, motility, morphology, and aneuploidies. Therefore, this systematic review has empirical evidence of behavior modification to avoid heat and prevent the risks of male infertility.
References
1. Hirsh A. Male subfertility. BMJ 2003;327:669-72.
2. Wolman I. Berek and Novak’s Gynecology 15th Edition: Lippincott Williams and Wilkins, 2012, 1560 pp, Hardcover, Rs. 2659 on www.flipkart.com, ISBN- 139788184736106, ISBN-10818473610X. J Obstet Gynaecol India 2014;64:150-1.
3. Oztekin U, Caniklioglu M, Sari S, et al. Evaluation of male infertility prevalence with clinical outcomes in middle Anatolian region. Cureus 2019;11:e5122.
4. Jerachotechueantaveechai T. Male Infertility. [Internet] 2014 [cited 2020 Sep 20]. Available from https://w1.med.cmu. ac.th/obgyn/index.php?option=com_
content&view=article&id=907:male-infer tility&catid=45&Itemid=561.
5. Vockel M, Riera-Escamilla A, Tuttelmann F, et al. The X chromosome and male infertility. Hum Genet 2021;140:203-15.
6. Kollin C, Ritzen EM. Cryptorchidism: a clinical perspective. Pediatr Endocrinol Rev 2014;11 Suppl 2:240-50.
7. Carlsen E, Andersson AM, Petersen JH, et al. History of febrile illness and variation in semen quality. Hum Reprod 2003;18: 2089-92.
8. Lane AR, Magallanes CA, Hackney AC. Reproductive dysfunction from exercise training: the exercise-hypogonadal male condition. Arch Med Deporte 2019;36:319-22.
9. Garolla A, Torino M, Sartini B, et al. Seminal and molecular evidence that sauna exposure affects human spermatogenesis. Hum Reprod 2013;28:877-85.
10. Verón GL, Tissera AD, Bello R, et al. Impact of age, clinical conditions, and lifestyle on routine semen parameters and sperm kinematics. Fertil Steril 2018;110:68-75.e4.
11. Murray KS, James A, McGeady JB, et al. The effect of the new 2010 World Health Organization criteria for semen analyses on male infertility. Fertil Steril 2012;98: 1428-31.
12. Wu YQ, Rao M, Hu SF, et al. Effect of transient scrotal hyperthermia on human sperm: an iTRAQ-based proteomic analysis. Reprod Biol Endocrinol 2020;18:83.
13. Abdelhamid MHM, Esquerre-Lamare C, Walschaerts M, et al. Experimental mild increase in testicular temperature has drastic, but reversible, effect on sperm aneuploidy in men: A pilot study. Reprod Biol 2019;19:189-94.
14. Ahmad G, Moinard N, Esquerré-Lamare C, et al. Mild induced testicular and epididymal hyperthermia alters sperm chromatin integrity in men. Fertil Steril 2012;97:546-53.
15. Sheynkin Y, Welliver R, Winer A, et al. Protection from scrotal hyperthermia in laptop computer users. Fertil Steril 2011;95:647-51.
16. Momen MN, Ananian FB, Fahmy IM, et al. Effect of high environmental temperature on semen parameters among fertile men. Fertil Steril 2010;93:1884-6.
17. Mínguez-Alarcón L, Gaskins AJ, Chiu YH, et al. Type of underwear worn and markers of testicular function among men attending a fertility center. Hum Reprod
2018;33:1749-56.
18. Van De Graaff, Kent M., Fox, et al. Concepts of Human Anatomy and Physiology. 3rd edition. Dubuque, Iowa: Wm. C. Brown Publishers;1992.p952-1020.
19. Skandhan KP, Rajahariprasad A. The process of spermatogenesis liberates significant heat and the scrotum has a role in body thermoregulation. Med Hypotheses 2007;68:303-7.
20. Ilacqua A, Izzo G, Emerenziani GP, et al. Lifestyle and fertility: the influence of stress and quality of life on male fertility. Reprod Biol Endocrinol 2018;16:115.
21. van der Horst G, Skosana B, Legendre A, et al. Cut-off values for normal sperm morphology and toxicology for automated analysis of rat sperm morphology and
morphometry. Biotech Histochem 2018;93:49-58.
22. Santiso R, Tamayo M, Gosálvez J, et al. DNA fragmentation dynamics allows the assessment of cryptic sperm damage in human: evaluation of exposure to ionizing radiation, hyperthermia, acidic pH and nitric oxide. Mutat Res 2012;734:41-9.
23. Mínguez-Alarcón L, Gaskins AJ, Chiu YH, et al. Type of underwear worn and markers of testicular function among men attending a fertility center. Hum Reprod
2018;3:1749-56.
24. Jurewicz J, Radwan M, Sobala W, et al. Lifestyle factors and sperm aneuploidy. Reprod Biol 2014;14:190-9.
25. Wang X, Liu F, Gao X, et al. Comparative proteomic analysis of heat stress proteins associated with rat sperm maturation. Mol Med Rep 2016;13:3547-52.
26. Sabés-Alsina M, Tallo-Parra O, Mogas MT, et al. Heat stress has an effect on motility and metabolic activity of rabbit spermatozoa. Anim Reprod Sci 2016;
173:18-23.
27. Osman MW, Nikolopoulos L, Haoula Z, et al. A study of the effect of the FertilMate™ scrotum cooling patch on male fertility. SCOP trial (scrotal cooling patch) - study protocol for a randomized controlled trial. Trials 2012;13:47.
28. Hjollund NH, Storgaard L, Ernst E, et al. Impact of diurnal scrotal temperature on semen quality. Reprod Toxicol 2002; 16:215-21.
29. Cullen T, Clarke ND, Hill M, et al. The health benefits of passive heating and aerobic exercise: To what extent do the mechanisms overlap? J Appl Physiol 2020;129:1304-09.
30. Sandella B, Hartmann B, Berkson D, et al. Testicular conditions in athletes: torsion, tumors, and epididymitis. Curr Sports Med Rep 2012;11:92-5.
31. Kumar N, Singh AK. Trends of male factor infertility, an important cause of infertility: A review of literature. J Hum Reprod Sci 2015;8:191-6.
2. Wolman I. Berek and Novak’s Gynecology 15th Edition: Lippincott Williams and Wilkins, 2012, 1560 pp, Hardcover, Rs. 2659 on www.flipkart.com, ISBN- 139788184736106, ISBN-10818473610X. J Obstet Gynaecol India 2014;64:150-1.
3. Oztekin U, Caniklioglu M, Sari S, et al. Evaluation of male infertility prevalence with clinical outcomes in middle Anatolian region. Cureus 2019;11:e5122.
4. Jerachotechueantaveechai T. Male Infertility. [Internet] 2014 [cited 2020 Sep 20]. Available from https://w1.med.cmu. ac.th/obgyn/index.php?option=com_
content&view=article&id=907:male-infer tility&catid=45&Itemid=561.
5. Vockel M, Riera-Escamilla A, Tuttelmann F, et al. The X chromosome and male infertility. Hum Genet 2021;140:203-15.
6. Kollin C, Ritzen EM. Cryptorchidism: a clinical perspective. Pediatr Endocrinol Rev 2014;11 Suppl 2:240-50.
7. Carlsen E, Andersson AM, Petersen JH, et al. History of febrile illness and variation in semen quality. Hum Reprod 2003;18: 2089-92.
8. Lane AR, Magallanes CA, Hackney AC. Reproductive dysfunction from exercise training: the exercise-hypogonadal male condition. Arch Med Deporte 2019;36:319-22.
9. Garolla A, Torino M, Sartini B, et al. Seminal and molecular evidence that sauna exposure affects human spermatogenesis. Hum Reprod 2013;28:877-85.
10. Verón GL, Tissera AD, Bello R, et al. Impact of age, clinical conditions, and lifestyle on routine semen parameters and sperm kinematics. Fertil Steril 2018;110:68-75.e4.
11. Murray KS, James A, McGeady JB, et al. The effect of the new 2010 World Health Organization criteria for semen analyses on male infertility. Fertil Steril 2012;98: 1428-31.
12. Wu YQ, Rao M, Hu SF, et al. Effect of transient scrotal hyperthermia on human sperm: an iTRAQ-based proteomic analysis. Reprod Biol Endocrinol 2020;18:83.
13. Abdelhamid MHM, Esquerre-Lamare C, Walschaerts M, et al. Experimental mild increase in testicular temperature has drastic, but reversible, effect on sperm aneuploidy in men: A pilot study. Reprod Biol 2019;19:189-94.
14. Ahmad G, Moinard N, Esquerré-Lamare C, et al. Mild induced testicular and epididymal hyperthermia alters sperm chromatin integrity in men. Fertil Steril 2012;97:546-53.
15. Sheynkin Y, Welliver R, Winer A, et al. Protection from scrotal hyperthermia in laptop computer users. Fertil Steril 2011;95:647-51.
16. Momen MN, Ananian FB, Fahmy IM, et al. Effect of high environmental temperature on semen parameters among fertile men. Fertil Steril 2010;93:1884-6.
17. Mínguez-Alarcón L, Gaskins AJ, Chiu YH, et al. Type of underwear worn and markers of testicular function among men attending a fertility center. Hum Reprod
2018;33:1749-56.
18. Van De Graaff, Kent M., Fox, et al. Concepts of Human Anatomy and Physiology. 3rd edition. Dubuque, Iowa: Wm. C. Brown Publishers;1992.p952-1020.
19. Skandhan KP, Rajahariprasad A. The process of spermatogenesis liberates significant heat and the scrotum has a role in body thermoregulation. Med Hypotheses 2007;68:303-7.
20. Ilacqua A, Izzo G, Emerenziani GP, et al. Lifestyle and fertility: the influence of stress and quality of life on male fertility. Reprod Biol Endocrinol 2018;16:115.
21. van der Horst G, Skosana B, Legendre A, et al. Cut-off values for normal sperm morphology and toxicology for automated analysis of rat sperm morphology and
morphometry. Biotech Histochem 2018;93:49-58.
22. Santiso R, Tamayo M, Gosálvez J, et al. DNA fragmentation dynamics allows the assessment of cryptic sperm damage in human: evaluation of exposure to ionizing radiation, hyperthermia, acidic pH and nitric oxide. Mutat Res 2012;734:41-9.
23. Mínguez-Alarcón L, Gaskins AJ, Chiu YH, et al. Type of underwear worn and markers of testicular function among men attending a fertility center. Hum Reprod
2018;3:1749-56.
24. Jurewicz J, Radwan M, Sobala W, et al. Lifestyle factors and sperm aneuploidy. Reprod Biol 2014;14:190-9.
25. Wang X, Liu F, Gao X, et al. Comparative proteomic analysis of heat stress proteins associated with rat sperm maturation. Mol Med Rep 2016;13:3547-52.
26. Sabés-Alsina M, Tallo-Parra O, Mogas MT, et al. Heat stress has an effect on motility and metabolic activity of rabbit spermatozoa. Anim Reprod Sci 2016;
173:18-23.
27. Osman MW, Nikolopoulos L, Haoula Z, et al. A study of the effect of the FertilMate™ scrotum cooling patch on male fertility. SCOP trial (scrotal cooling patch) - study protocol for a randomized controlled trial. Trials 2012;13:47.
28. Hjollund NH, Storgaard L, Ernst E, et al. Impact of diurnal scrotal temperature on semen quality. Reprod Toxicol 2002; 16:215-21.
29. Cullen T, Clarke ND, Hill M, et al. The health benefits of passive heating and aerobic exercise: To what extent do the mechanisms overlap? J Appl Physiol 2020;129:1304-09.
30. Sandella B, Hartmann B, Berkson D, et al. Testicular conditions in athletes: torsion, tumors, and epididymitis. Curr Sports Med Rep 2012;11:92-5.
31. Kumar N, Singh AK. Trends of male factor infertility, an important cause of infertility: A review of literature. J Hum Reprod Sci 2015;8:191-6.
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Published
2021-08-31
How to Cite
1.
Danviboon K, Sripradite S, Tangbumrungkul P, Sangkanjanavanich C, Pruksaseat C, Jeamanukoolkit P, Saijai K, Pongputcharapun K, Bhubhanil S, Lapmanee S. The effects of heat on sperm quality and male infertility: A systematic review. J Med Health Sci [Internet]. 2021 Aug. 31 [cited 2024 Nov. 22];28(2):198-20. Available from: https://he01.tci-thaijo.org/index.php/jmhs/article/view/251573
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Review article (บทความวิชาการ)
