The use of herbal medicine to treat hypertension in hospitals under the office of the Permanent Secretary of the Ministry of Public Health
Keywords:
Herbal medicines, hypertension, , hospitals, Ministry of Public HealthAbstract
The situation and the problems of hypertension have a tendency to increase and escalate. Since modern medicine has limitations in terms of the cost, outcome and side effects of treatment, complementary medicine can be used to treat hypertensive patients. Therefore, this study aims to survey the use of herbal medicine to treat hypertension in hospitals under the office of the Permanent Secretary of the Ministry of Public Health. The sample consisted of 873 Thai traditional doctors affiliated with hospitals under the office of the Permanent Secretary of the Ministry of Public Health. The data were collected by telephone interviews between October 2020 to January 2021. The data were analyzed by content analysis and the use of descriptive statistics. The results revealed that 264 hospitals (30.24%) used herbal medicines to treat hypertension. Most hospitals have used complementary medicine for less than five years (186 hospitals, 21.31%) and most had 1-5 service recipients per month (109 hospitals, 12.49%). In total, 32 herbal recipes were used for hypertensive treatment. The three most popular herbal medicines were Yahom Thepajit (155 hospitals, 58.71%), Yahom Nalwagod (84 hospitals, 31.82%) and Roselle herbal tea-Hibiscus sabdariffa L. (64 hospitals, 24.24%). From the results, it can be assumed that few hospitals under the office of the Permanent Secretary of the Ministry of Public Health used herbal medicines to treat hypertensive patients. Therefore, research should be conducted with herbal treatment for hypertension, training and used as a database for policy planning among Thai traditional medicine personnel in government services on the use of herbal medicines.
References
1. Wacharasin S. Hypertension and rational drug use. 1st ed. Bangkok: Media and Publishing Center Kaew Chao Chom Suan Sunandha Rajabhat University; 2017.
2. Karoonngamphan M, Suvaree S. Reducing the risk of hypertension: The important role of nurses in empowering clients. Songklanagarind Nurs 2016;36:222-33.
3. Wichai C, Poldongnauk S, Sawanyawisuth K. Hypertension. 1st ed. Khonkaen: Health promotion unit social medicine work Srinagarind Hospital; 2015.
4. Division of Non-communicable diseases, Department of Disease Control, Ministry of Public Health. Number and rate of patients in 2016-2018 [internet]. Nonthaburi; 2019. Available from http://www.thaincd.com/2016/mission/documents.php?tid=32&gid=1-020.
5. Institute of Medical Technology Research and Evaluation, Department of Medical Services, Ministry of Public Health. Review of current affairs and non-communicable
disease service models 2014. 1st ed. Nonthaburi: Art qualified company limited.; 2014.
6. Office of Alternative Medicine, Department of Development of Thai Traditional and Alternative Medicine. Handbook of care for patients with hypertension with integrated medicine. 1st ed. Nonthaburi Office of Alternative Medicine, Department of Development of Thai Traditional and Alternative Medicine; n.d.
7. Academic and Knowledge Division Academic and Planning Division. Department of Thai Traditional and Alternative Medicine. Herbal medicine consumption (Information on consumption of herbal medicines, fiscal year 2021 [internet]. Nonthaburi; 2021. Available from http://hs.dtam. moph.go.th/.
8. The Policy and Strategy Section, Bureau of Non-Communicable Disease, Ministry of Public Health, editors. 5-Year National NCDs Prevention and Control Strategic and Action Plan (2017-2021). 1st ed. Bangkok: Emotion Art Co., Ltd.; 2019.
9. Peter BJ, Halimatu K, Abdulai JB, et al. Herbal medicine use among hypertensive patients attending public and private health facilities in Freetown Sierra Leone. Complement Ther Clin Pract 2018;31:7-15.
10. Heamachan P, Rammanop N, Lohitthai L. Knowledge, attitude and behavior on herbs using among diabetic and hypertensive patients at Family practice center, Phra Nakhon Si Ayutthaya hospital. JPMAT 2019;9:87-100.
11. Unjana R, Leemingsawat W. Knowledge, attitude and behavior of using alternative medicine in Thai people. JSSH 2016;17: 70-83.
12. Picheansoonthon C, Tanahavadhana S, Supalaknaree S, et al. Hypertension in Thai traditional medicine perspective. The Journal of the Royal Society of Thailand 2011;36:221-30.
13. Bahuguna Y, Juyal V, Rawat MSM, et al. Diuretic activity of flowers of Jasminum auriculatum Vahl. JPR 2009;2:215-6.
14. Polsan N. Effect of Fragrant extract on heart function isolated from rat body with blood vessels [Dissertation]. Bangkok: Chulalongkorn University; 2004.
15. Tangkomsaengtong C, Arunakul I, Itharat A. Preliminary study on effect and safety of Roselle extract tablets for treating patient with stage 1 hypertension. Thai J Pharm Prac 2020;12:913-22.
16. Bunbupha S, Wunpathe C, Maneesai P, et al. Carthamus tinctorius L. extract improves hemodynamic and vascular alterations in a rat model of renovascular hypertension
through Ang II-AT 1 R-NADPH oxidase pathway. Ann Anat 2018;216:82-9.
17. Nurul MM, Aidiahmad D, Mohd ZA, et al. Vascular reactivity concerning Orthosiphon stamineus Benth-mediated antihypertensive in aortic rings of spontaneously hypertensive rats. Int J Vasc Med 2013; doi:10.1155/2013/456852.
18. Luednakrob N. Effect of gotu kola extract (Centella asiatica (L.) Urban.) On hypotensive effect of rats induced hypertension [Dissertation]. Khonkaen:Khon Kaen University; 2002.
19. Ali L, Khan AK, Mamun MI, et al. Studies on hypoglycemic effects of fruit pulo, seed, and whole plant of Momordica charantia on normal and diabetic model rats. Planta Med 1993;59:408-12.
20. Thongsaard W, Marsden CA, Morris P, et al. Effect of Thunbergia laurifolia, a Thai natural product used to treat drug addiction, on cerebral activity detected by functional magnetic resonance imaging in the rat. Psychopharmacology (Berl) 2005;180(4):752-60.
21. Jansakul C. The loosening effect of the bronchi and cardiovascular activity of high purity substances isolated from Tinospora crispa stem. Bangkok: Thailand Science
Research and Innovation; 2009.
22. Christopher E, Nyebuk D, Ernest A. Phytoconstituents and diuretic activity of Cymbopogon citratus leaf infusions in humans. J Coast Life Med 2014;2:704-13.
23. Ghayur MN, Gilani AH, Afridi MB, et al. Cardiovascular effects of ginger aqueous extract and its phenolic constituents are mediated through multiple pathways. Vascul Pharmacol 43:234-41.
24. Pantoja CV, Chiang LCH, Norris BC, et al. Diuretic, Natriuretic and hypotensive effects produced by Allium sativum (garlic) in anesthetized dogs. J Ethnopharmacol
1991;31:325-31.
25. Dytha AD, Sri M. Influence of mulberry leaf extract (Morus alba L.) on diuretic activity of male white Wistar strain rat. Drug Invention Today 2018;10:3811-3.
26. Kartick CP, Ria B, Anupama M, et al. Tissue culture of the plant Pluchea indica (L.) Less. and evaluation of diuretic potential of its leaves. Orient Pharm Exp Med
2007;7:197-204.
27. Zhang C, Kuroyangi M, Tan BKH. Cardiovascular activity of 14-deoxy-11,12 didehydroandrographolide in the anaesthetised rat and isolated right atria. Pharmacol Res 1998;38:413-7.
28. Jansakul C, Srichanbarn A, Saelee A. Some pharmacological studies of a hypotensive fraction from Derris scandens. J Sci Soc Thai 1997;23:323-34.
29. Koichi K, Yuko K, Yumiko S, et al. Purification and Identification of Angiotensin I-Converting Enzyme Inhibitor from Morokheiya (Corchorus olitorius). Food Sci. Technol. lnt. Tokyo 1998; doi:10.3136/fsti9596t9798.4.223.
30. Announcement of the Ministry of Public Health Re: Traditional Home Medicines, 2013. Government Gazette Volume 130, Special Part 21 (dated February 14, 2013).
31. Committee for preparing Thai herbal medicine In the Committee for the Protection and Promotion of Thai Traditional Medicine Knowledge. Thai herbal medicine reference textbook, volume 2 in honor of HRH Princess Maha Chakri Sirindhorn. Siam Boromrajakumari on the auspicious occasion to celebrate the 60th birthday. 1st ed. Bangkok: Amarin Printing and Publishing Public Company Limited; 2015.
32. Kitiyamas S. Effect of Thai drug, Homthepjit drug formula on sleep quality in people with insomnia [Dissertation]. Chiangrai: Mae Fah Luang University; 2015.
33. Laura P, Rosa MB, Angelo G, et al. Sleep loss and hypertension: A systematic review. Curr Pharm Des 2013;19:2409-19.
34. Soonthornchareonnon N. Yahom:A scientifically proven intellectual legacy [internet]. Nonthaburi; n.d. Available from https://pharmacy.mahidol.ac.th/th/
knowledge/article/283/contact.php.
35. Polsan N. Effect of Fragrant extract on heart function isolated from rat body with blood vessels [Dissertation]. Bangkok: Chulalongkorn University; 2004.
36. Maekasuwannadit T, Montakantikul P, Suthisisang C, et al. Textbook of pharmacotherapy. 2nd ed. Bangkok: holistic publishing; 2007.
37. Intarit P, Pava KK, Itharat A, et al. Comparative study on the efficacy and side effects of Hibiscus sabdariffa Linn. extract Versus simvastatin in reducing blood lipids levels on hyperlipidemias patient (Clinical Trial Phase II). Thammasat Medical Journal 2012;12:506-17.
38. Thanasatirakul P. The effects of roselle flower tea (Hibiscus sabdariffa extract) on home blood pressure in patients with mild hypertension : a randomized double blinded placebo controlled trial [Dissertation]. Bangkok: Chulalongkorn University; 2011.
39. Jalalyazdi M, Ramezani J, Izadi-Moud A, et al. Effect of hibiscus sabdariffa on blood pressure in patients with stage 1 hypertension. J Adv Pharm Technol Res 201910(3):107-11.
2. Karoonngamphan M, Suvaree S. Reducing the risk of hypertension: The important role of nurses in empowering clients. Songklanagarind Nurs 2016;36:222-33.
3. Wichai C, Poldongnauk S, Sawanyawisuth K. Hypertension. 1st ed. Khonkaen: Health promotion unit social medicine work Srinagarind Hospital; 2015.
4. Division of Non-communicable diseases, Department of Disease Control, Ministry of Public Health. Number and rate of patients in 2016-2018 [internet]. Nonthaburi; 2019. Available from http://www.thaincd.com/2016/mission/documents.php?tid=32&gid=1-020.
5. Institute of Medical Technology Research and Evaluation, Department of Medical Services, Ministry of Public Health. Review of current affairs and non-communicable
disease service models 2014. 1st ed. Nonthaburi: Art qualified company limited.; 2014.
6. Office of Alternative Medicine, Department of Development of Thai Traditional and Alternative Medicine. Handbook of care for patients with hypertension with integrated medicine. 1st ed. Nonthaburi Office of Alternative Medicine, Department of Development of Thai Traditional and Alternative Medicine; n.d.
7. Academic and Knowledge Division Academic and Planning Division. Department of Thai Traditional and Alternative Medicine. Herbal medicine consumption (Information on consumption of herbal medicines, fiscal year 2021 [internet]. Nonthaburi; 2021. Available from http://hs.dtam. moph.go.th/.
8. The Policy and Strategy Section, Bureau of Non-Communicable Disease, Ministry of Public Health, editors. 5-Year National NCDs Prevention and Control Strategic and Action Plan (2017-2021). 1st ed. Bangkok: Emotion Art Co., Ltd.; 2019.
9. Peter BJ, Halimatu K, Abdulai JB, et al. Herbal medicine use among hypertensive patients attending public and private health facilities in Freetown Sierra Leone. Complement Ther Clin Pract 2018;31:7-15.
10. Heamachan P, Rammanop N, Lohitthai L. Knowledge, attitude and behavior on herbs using among diabetic and hypertensive patients at Family practice center, Phra Nakhon Si Ayutthaya hospital. JPMAT 2019;9:87-100.
11. Unjana R, Leemingsawat W. Knowledge, attitude and behavior of using alternative medicine in Thai people. JSSH 2016;17: 70-83.
12. Picheansoonthon C, Tanahavadhana S, Supalaknaree S, et al. Hypertension in Thai traditional medicine perspective. The Journal of the Royal Society of Thailand 2011;36:221-30.
13. Bahuguna Y, Juyal V, Rawat MSM, et al. Diuretic activity of flowers of Jasminum auriculatum Vahl. JPR 2009;2:215-6.
14. Polsan N. Effect of Fragrant extract on heart function isolated from rat body with blood vessels [Dissertation]. Bangkok: Chulalongkorn University; 2004.
15. Tangkomsaengtong C, Arunakul I, Itharat A. Preliminary study on effect and safety of Roselle extract tablets for treating patient with stage 1 hypertension. Thai J Pharm Prac 2020;12:913-22.
16. Bunbupha S, Wunpathe C, Maneesai P, et al. Carthamus tinctorius L. extract improves hemodynamic and vascular alterations in a rat model of renovascular hypertension
through Ang II-AT 1 R-NADPH oxidase pathway. Ann Anat 2018;216:82-9.
17. Nurul MM, Aidiahmad D, Mohd ZA, et al. Vascular reactivity concerning Orthosiphon stamineus Benth-mediated antihypertensive in aortic rings of spontaneously hypertensive rats. Int J Vasc Med 2013; doi:10.1155/2013/456852.
18. Luednakrob N. Effect of gotu kola extract (Centella asiatica (L.) Urban.) On hypotensive effect of rats induced hypertension [Dissertation]. Khonkaen:Khon Kaen University; 2002.
19. Ali L, Khan AK, Mamun MI, et al. Studies on hypoglycemic effects of fruit pulo, seed, and whole plant of Momordica charantia on normal and diabetic model rats. Planta Med 1993;59:408-12.
20. Thongsaard W, Marsden CA, Morris P, et al. Effect of Thunbergia laurifolia, a Thai natural product used to treat drug addiction, on cerebral activity detected by functional magnetic resonance imaging in the rat. Psychopharmacology (Berl) 2005;180(4):752-60.
21. Jansakul C. The loosening effect of the bronchi and cardiovascular activity of high purity substances isolated from Tinospora crispa stem. Bangkok: Thailand Science
Research and Innovation; 2009.
22. Christopher E, Nyebuk D, Ernest A. Phytoconstituents and diuretic activity of Cymbopogon citratus leaf infusions in humans. J Coast Life Med 2014;2:704-13.
23. Ghayur MN, Gilani AH, Afridi MB, et al. Cardiovascular effects of ginger aqueous extract and its phenolic constituents are mediated through multiple pathways. Vascul Pharmacol 43:234-41.
24. Pantoja CV, Chiang LCH, Norris BC, et al. Diuretic, Natriuretic and hypotensive effects produced by Allium sativum (garlic) in anesthetized dogs. J Ethnopharmacol
1991;31:325-31.
25. Dytha AD, Sri M. Influence of mulberry leaf extract (Morus alba L.) on diuretic activity of male white Wistar strain rat. Drug Invention Today 2018;10:3811-3.
26. Kartick CP, Ria B, Anupama M, et al. Tissue culture of the plant Pluchea indica (L.) Less. and evaluation of diuretic potential of its leaves. Orient Pharm Exp Med
2007;7:197-204.
27. Zhang C, Kuroyangi M, Tan BKH. Cardiovascular activity of 14-deoxy-11,12 didehydroandrographolide in the anaesthetised rat and isolated right atria. Pharmacol Res 1998;38:413-7.
28. Jansakul C, Srichanbarn A, Saelee A. Some pharmacological studies of a hypotensive fraction from Derris scandens. J Sci Soc Thai 1997;23:323-34.
29. Koichi K, Yuko K, Yumiko S, et al. Purification and Identification of Angiotensin I-Converting Enzyme Inhibitor from Morokheiya (Corchorus olitorius). Food Sci. Technol. lnt. Tokyo 1998; doi:10.3136/fsti9596t9798.4.223.
30. Announcement of the Ministry of Public Health Re: Traditional Home Medicines, 2013. Government Gazette Volume 130, Special Part 21 (dated February 14, 2013).
31. Committee for preparing Thai herbal medicine In the Committee for the Protection and Promotion of Thai Traditional Medicine Knowledge. Thai herbal medicine reference textbook, volume 2 in honor of HRH Princess Maha Chakri Sirindhorn. Siam Boromrajakumari on the auspicious occasion to celebrate the 60th birthday. 1st ed. Bangkok: Amarin Printing and Publishing Public Company Limited; 2015.
32. Kitiyamas S. Effect of Thai drug, Homthepjit drug formula on sleep quality in people with insomnia [Dissertation]. Chiangrai: Mae Fah Luang University; 2015.
33. Laura P, Rosa MB, Angelo G, et al. Sleep loss and hypertension: A systematic review. Curr Pharm Des 2013;19:2409-19.
34. Soonthornchareonnon N. Yahom:A scientifically proven intellectual legacy [internet]. Nonthaburi; n.d. Available from https://pharmacy.mahidol.ac.th/th/
knowledge/article/283/contact.php.
35. Polsan N. Effect of Fragrant extract on heart function isolated from rat body with blood vessels [Dissertation]. Bangkok: Chulalongkorn University; 2004.
36. Maekasuwannadit T, Montakantikul P, Suthisisang C, et al. Textbook of pharmacotherapy. 2nd ed. Bangkok: holistic publishing; 2007.
37. Intarit P, Pava KK, Itharat A, et al. Comparative study on the efficacy and side effects of Hibiscus sabdariffa Linn. extract Versus simvastatin in reducing blood lipids levels on hyperlipidemias patient (Clinical Trial Phase II). Thammasat Medical Journal 2012;12:506-17.
38. Thanasatirakul P. The effects of roselle flower tea (Hibiscus sabdariffa extract) on home blood pressure in patients with mild hypertension : a randomized double blinded placebo controlled trial [Dissertation]. Bangkok: Chulalongkorn University; 2011.
39. Jalalyazdi M, Ramezani J, Izadi-Moud A, et al. Effect of hibiscus sabdariffa on blood pressure in patients with stage 1 hypertension. J Adv Pharm Technol Res 201910(3):107-11.
Downloads
Published
2021-08-31
How to Cite
1.
Bunpean A, Subhadhirasakul S, Neamsuvan O, Siriyong T. The use of herbal medicine to treat hypertension in hospitals under the office of the Permanent Secretary of the Ministry of Public Health. J Med Health Sci [Internet]. 2021 Aug. 31 [cited 2024 Nov. 6];28(2):27-42. Available from: https://he01.tci-thaijo.org/index.php/jmhs/article/view/251547
Issue
Section
Original article (บทความวิจัย)
