Outcome of cervical intraepithelial neoplasia treatment by thermal ablation in National Cancer Institute


  • Supakorn Pitakkarnkul
  • Sujira Foongfaung


cervical intraepithelial neoplasia, thermal ablation, outcome


Cervical cancer is a major cancer of women in Thailand. This disease has a pre-invasive stage called cervical intraepithelial neoplasia (CIN) can be treated by Thermal ablation. Thailand has now been using this method. This retrospective study collected data from medical records of fifty-eight women with a diagnosis of CIN 1 that was treated with Thermal ablation at Gynaecological outpatient clinic of the National Cancer Institute. It was found that the cure rate after the treatment for 12 months was 86.2 percent. Few side effects of treatment were reported. Therefore, the thermal ablation is an effective method for treating CIN 1 lesions.


Download data is not yet available.


1. Pongnikorn D , Suwanrungruang K , Buasom R . Cancer Incidence in Thailand .In:Imsamran W, Pattatang A, Supattagorn P, editors. Cancer in Thailand. 1sted. Bangkok: National Cancer Institute;2018. p.7
2. Arends MJ, Buckley CH, Wells M. Aetiology, pathogenesis, and pathology of cervical neoplasia. J Clin Pathol 1998;51:96–103.
3. Papoutsis D, Underwood M, Parry-Smith W, et al. Comparison of cure rates in women treated with cold-coagulation versus LLETZ cervical treatment for CIN2-3 on pretreatment cervical punch biopsies: A retrospective cohort study. Arch Gynecol Obstet 2017;295:979-86.
4. Santos CL, Torres J, Sanchez J, et al. Lack of effectiveness of CO2 cryotherapy for treatment of CIN. Int J Gynaecol Obstet 2004;87:44-5.
5. Maza M, Schocken CM, Bergman KL, et al. Cervical precancer treatment in low- and middle-income countries: a technology overview. J Glob Oncol 2017;3:400–8.
6. Sellors JW, Sankaranarayanan R,editors. Colposcopy and treatment of cervical intraepithelial neoplasia: a beginners’ manual. Lyon:International Agency for Research on Cancer; 2003.
7. Dolman L, Sauvaget C, Muwonge R, et al. Meta-analysis of the efficacy of thermal ablation as a treatment method for cervical intraepithelial neoplasia: a systematic review. BJOG 2014;121:929–42.
8. Zawislak A, Price JH, McClelland HR, et al. Efficacy of cervical intraepithelial neoplasia (CIN) treatment by thermal ablation. Ulster Med J 2003;72:10-5.
9. Parry-Smith W, Underwood M, De Bellis-Ayres S, et al. Success rate of thermal ablation for the treatment of cervical intraepithelial neoplasia. J Low Genit Tract Dis 2015;19:17-21.
10. A Wyse, W A Seah, J O'Neill, et al. The use of cold coagulation for the treatment of cervical intraepithelial neoplasia. Ir Med J 2017;110:565.
11. Kyrgiou M, Athanasiou A, Kalliala IEJ, et al. Obstetric outcomes after conservative treatment for cervicalintraepithelial lesions and early invasive disease. Cochrane Database Syst Rev 2017;11:CD012847.






Short Communication (บทความวิจัยอย่างสั้น)