Echocardiography Evaluation of the Left Ventricular Mass Index (LVMI) and Geometrical Pattern in Pre-Eclampsia and Pregnancy- Induced Hypertension Patients
DOI:
https://doi.org/10.31584/jhsmr.20241048Keywords:
Lv function, Lv geometrical patterns, Lv mass index, pregnant women, proteinuriaAbstract
Objective: The objective of this study was to evaluate the degree of hypertrophy and its geometrical patterns in hypertensive (HTN) pregnant women, with or without proteinuria.
Material and Methods: Data from 88 pregnant women was analyzed., consecutively. Both clinical and echocardiographic data between normotensive and hypertensive women, with and without proteinuria, were compared.
Results: Hypertensive women, with and without proteinuria, have a higher LV mass indexed by height than normotensive women (108.1±64.6 g/m vs. 76.5±24.8 g/m vs. 68.7±17.1 g/m, p-value=0.001).
Conclusion: This research shows that women that suffer from pre-eclampsia and pregnancy-induced hypertension show significant subclinical remodelling of the left ventricle, encompassing structural and functional changes, compared to those with normotensive pregnant women.
References
Vinayagam D, Thilaganathan B, Stirrup O, Mantovani E, Khalil A. Maternal hemodynamics in normal pregnancy: reference ranges and role of maternal characteristics. Ultrasound Obstet Gynecol 2018;51:665–71. doi: 10.1002/uog.17504.
Meah VL, Cockcroft JR, Backx K, Shave R, Stöhr EJ. Cardiac output and related haemodynamics during pregnancy: a series of meta-analyses. Heart 2016;102:518–26. doi: 10.1136/heartjnl-2015-308476.
Melchiorre K, Sharma R, Khalil A, Thilaganathan B. Maternal cardiovascular function in normal pregnancy: evidence of maladaptation to chronic volume overload. Hypertension 2016;67:754–62. doi: 10.1161HYPERTENSIONAHA.115.06667.
Savu O, Jurcuţ R, Giuşcă S, van Mieghem T, Gussi I, Popescu BA, et al. Morphological and functional adaptation of the maternal heart during pregnancy. Circ Cardiovasc Imaging 2012;5:289–97. doi: 10.1161/CIRCIMAGING.111.970012.
National High Blood Pressure Education Program Working Group. Report of the national high blood pressure education program working group on high blood pressure in pregnancy. Am J Obstet Gynecol 2000;183:S1-22. doi: 10.1016/s0002-9378(00)40820-3.
Stuart JJ, Tanz LJ, Rimm EB, Spiegelman D, Missmer SA, Mukamal KJ, et al. Cardiovascular risk factors mediate the longterm maternal risk associated with hypertensive disorders of pregnancy. J Am Coll Cardiol 2022;79:1901-13.
Thilaganathan B, Kalafat E. Cardiovascular system in preeclampsia and beyond. Hypertension 2019;73:522-31. doi: 10.1161/HYPERTENSIONAHA.118.11191.
Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, et al. Chamber quantification writing group; American society of echocardiography's guidelines and standards committee; European association of echocardiography. recommendations for chamber quantification: a report from the american society of echocardiography's guidelines and standards committee and the chamber quantification writing group, developed in conjunction with the European association of echocardiography, a branch of the European society of cardiology. J Am Soc Echocardiogr 2005;18:1440–63.
Yeomans ER, Hankins GD. Cardiovascular physiology and invasive cardiac monitoring. Clin Obstet Gynecol 1989;32:2-12. doi: 10.1097/00003081-198903000-00004.
Vanoppen A, Stigter R, Bruinse H. Cardiac output in normal pregnancy: a critical review. Obstet Gynecol 1996;87:310-8.
Im S, Jung H, Park S, Shin G, Lee W. Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension. Korean Circ J 1995;25:423.
Sánchez RA, Glenny JE, Marcó E, Voto LS, Lapidus AM, Iglesias GH, et al. Two-dimensional and M-mode echocardiographic findings in hypertensive pregnant women. Am J Obstet Gynecol 1986;154:910-3.
Thompson JA, Hays PM, Sagar KB, Cruikshank DP. Echocardiographic left ventricular mass to differentiate chronic hypertension from preeclampsia during pregnancy. Am J Obstet Gynecol 1986;155:994-9.
Vazquez Blanco M, Grosso O, Bellido CA, Iaviecoli OR, Berensztein CS, Ruda Vega H, et al. Left ventricular geometry in pregnancy-induced hypertension. Am J Hypertens 2000;13:226-30.
Cong J, Fan T, Yang X, Shen J, Cheng G, Zhang Z. Maternal cardiac remodeling and dysfunction in preeclampsia: a threedimensional speckle-tracking echocardiography study. Int J Cardiovasc Imaging 2015;31:1361-8.
Ganau A, Devereux RB, Roman MJ, de Simone G, Pickering TG, Saba PS, et al. Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension. J Am Coll Cardiol 1992;19:1550-8.
Soh JB, Shon SS, Kim SH, Jeong JW, Park YK, Park OK. Relation of left ventricular mass to body size and left ventricular wall stress in normal adults. Korean Circ J 1996;26:69-77.
Park SW. Multicenter trial for estimation of normal values of echocardiographic indices in Korea. Korean Circ J 2000;30:373.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
